Details of the Drug Formulations

General Information of Drug (ID: DM3JDRP)

• Drug Name: Cladribine Drug Info
• Synonyms: Chlorodeoxyadenosine; Cladarabine; Cladaribine; Cladribina; Cladribinum; CldAdo; Leustat; Leustatin; Litak; Movectro;Mylinax; CL9; RWJ 26251; Leustatin (TN); RWJ-26251; Cladribine [USAN:INN:BAN]; RWJ-26251-000; Cladribine (JAN/USAN/INN); Leustatin, 2-chlorodeoxyadenosine, Cladribine; Adenosine, 2-chloro-2'-deoxy; (2R,3S,5R)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol; 2 Chlorodeoxyadenosine; 2'-Deoxy-2-chloroadenosine; 2-CdA; 2-Chloro-2'-deoxy-beta-adenosine; 2-Chloro-2'-deoxyadenosine; 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine; 2-Chlorodeoxyadenosine; 2-chloro-6-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl)purine; 2-chloro-deoxyadenosine

Indication

Disease Entry	ICD 11	Status	REF
Hairy cell leukaemia	2A82.2	Approved	[1]
Multiple sclerosis	8A40	Phase 3	[2]
Relapsing-remitting multiple sclerosis	8A40.0	Phase 3	[3]

• Therapeutic Class: Anticancer Agents
• Cross-matching ID:
  PubChem CID: 20279
  ChEBI ID: CHEBI:567361
  CAS Number: 4291-63-8
  TTD ID: D05GJW
  VARIDT ID: DR00087
  INTEDE ID: DR1918
  ACDINA ID: D00951

Full List of Drug Formulations Containing This Drug

Cladribine 10mg tablet

Company	Formulation ID	FDA Description
Emd Serono	F23688	Hydroxypropyl Betadex; Magnesium Stearate; Sorbitol

Cladribine 1mg/ml injectable

Company	Formulation ID	FDA Description
Janssen Pharms	F23689	Sodium Chloride

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4799).
• [2] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [3] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)