Details of the Drug Formulations

General Information of Drug (ID: DM3NXRU)

• Drug Name: Timolol Drug Info
• Synonyms: Aquanil; Betim; Betimol; Blocadren; Istalol; Optimol; Proflax; TIM; Temserin; Tenopt; Timacar; Timololum; Timopic; Timoptol; Timolol GFS; Timolol [USAN]; Timoptic OcuDose; Apo-Timol; Apo-Timop; Betimol (TN); Blocadren (TN); Istalol (TN); MK-950; Novo-Timol; Nu-Timolol; Phoxal-timolol; Tim-AK; Timolol (INN); Timolol (TN); Timololum [INN-Latin]; Timoptic (TN); Timoptic-XE; Apo-Timol (TN); Apo-Timop (TN); Gen-Timolol (TN); L-714,465; Nu-Timolol (TN); PMS-Timolol (TN); Phoxal-timolol (TN); Tim-AK (TN); Timoptic OcuDose. (TN); Timoptic-XE (TN); S(-)-Timolol maleate; Timolol Maleate, (1:1) Salt; S-(-)-3-(3-tert-Butylamino-2-hydroxypropoxy)-4-morpholino-1,2,5-thiadiazole; (-)-3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole; (2S)-1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol; (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol; (2S)-1-[(1,1-dimethylethyl)amino]-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol; (S)-1-(1,1-(Dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol; (S)-1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol; (S)-timolol

Indication

Disease Entry	ICD 11	Status	REF
High blood pressure	BA00	Approved	[1]
Ocular hypertension	9C61.01	Approved	[2]

• Therapeutic Class: Antiarrhythmic Agents
• Cross-matching ID:
  PubChem CID: 33624
  ChEBI ID: CHEBI:9599
  CAS Number: 26839-75-8
  TTD ID: D05UVD
  VARIDT ID: DR00900
  INTEDE ID: DR1595
  ACDINA ID: D00677

Full List of Drug Formulations Containing This Drug

Timolol 10 mg tablet

Company	Formulation ID	FDA Description
Mylan Pharamceuticals	F21098	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
Bryant Ranch Prepack	F21099	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose; Starch, corn

Timolol 20 mg tablet

Company	Formulation ID	FDA Description
Mylan Pharamceuticals	F21100	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn

Timolol 5 mg tablet

Company	Formulation ID	FDA Description
Avera McKennan Hospital; Mylan Pharamceuticals	F21101	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn

Timolol Maleate eq 0.25% base solution

Company	Formulation ID	FDA Description
Valeant Pharms Intl	F23356	Monobasic; Dibasic Sodium Phosphate; Sodium Hydroxide; Purified Water; Benzalkonium Chloride

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 565).
• [2] Timolol FDA Label