Details of the Drug Formulations

General Information of Drug (ID: DM4WVC5)

• Drug Name: lifitegrast Drug Info
• Synonyms: Lifitegrast; Xiidra; 1025967-78-5; SAR-1118; SAR 1118; UNII-038E5L962W; CHEMBL2048028; 038E5L962W; (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid; (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid;(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid; SAR-1118; SAR-1119; SHP606; SPD606

Indication

Disease Entry	ICD 11	Status	REF
Dry eye disease	9E1Z	Approved	[1]
Allergic conjunctivitis	9A60.02	Phase 3	[2]

• Cross-matching ID:
  PubChem CID: 11965427
  ChEBI ID: CHEBI:133023
  CAS Number: 1025967-78-5
  TTD ID: D0Q9EV
  VARIDT ID: DR00072
  ACDINA ID: D01208

Full List of Drug Formulations Containing This Drug

Lifitegrast 50 mg/ml solution

Company	Formulation ID	FDA Description
Novartis Pharmaceuticals Corporation	F23210	Sodium Chloride; Sodium Phosphate Dibasic Anhydrous; Sodium Thiosulfate Pentahydrate; Water For Injection; Sodium Hydroxide; Hydrochloric Acid

References

• [1] 2016 FDA drug approvals. Nat Rev Drug Discov. 2017 Feb 2;16(2):73-76.
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7533).