Details of the Drug Formulations

General Information of Drug (ID: DM5I621)

• Drug Name: Methyldopa Drug Info
• Synonyms: AMD; Aldometil; Aldomin; Alphamethyldopa; Baypresol; Becanta; Dopamet; Dopamethyperpax; Dopatec; Dopegit; Dopegyt; Dopergit; Grospisk; Hyperpax; Hypolag; Medomet; Medopa; Medopal; Medopren; Methoplain; Methyldopum; Metildopa; Novomedopa; Presinol; Presolisin; Sedometil; Sembrina; Alpha medopa; Methyl dopa; Methyldopa anhydrous; Aldoril D30; Aldoril D50; Bayer 1440 L; LT00847269; MK 351; Aldomet (TN); Aldoril (TN); Alpha-Methyl dopa; Alpha-Methyldihydroxyphenylalanine; Alpha-Methyldopa; Apo-Methyldopa; Dopamet (TN); Dopegyt (TN); L-Methyl Dopa; L-Methyldopa; METHYL DOPA (SEE ALSO METHYL DOPA SESQUIHYDRATE); MK-351; Methyldopa (INN); Methyldopa (anhydrous); Methyldopum [INN-Latin]; Metildopa [INN-Spanish]; Mk. b51; Nr.C 2294; Nu-Medopa; Alpha-Methyldopa (VAN); L-alpha-Methyl DOPA; L-alpha-Methyldopa; Methyl-L-dopa; Aldoril, Dopamet, Dopegyt, Methyldopa; L-(alpha-Md); Methyldopa (L,-); Alpha-Methyl-L-3,4-dihydroxyphenylalanine; L-alpha-Methyl-3,4-dihydroxyphenylalanine; L-3-(3,4-Dihydroxyphenyl)-2-methylalanine; Levo-3-(3,4-Dihydroxyphenyl)-2-methylalanine; Alpha-Methyl-beta-(3,4-dihydroxyphenyl)-L-alanine; L(-)-beta-(3,4-Dihydroxyphenyl)-alpha-methylalanine; L-2-Amino-2-methyl-3-(3,4-dihydroxyphenyl)propionic acid; L-(-)-3-(3,4-Dihydroxyphenyl)-2-methylalanine; L-(-)-alpha-Methyl-beta-(3,4-dihydroxyphenyl)alanine; (-)-3-(3,4-Dihydroxyphenyl)-2-Methyl-L-Alanine Sesqui-Hydrate; (2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid; (S)-(-)-alpha-Methyldopa; 3-(3,4-DIHYDROXYPHENYL)-2-METHYL-L-ALANINE; 3-Hydroxy-.alpha.-methyl-L-tyrosine; 3-Hydroxy-alpha-methyl-L-tyrosine

Indication

Disease Entry	ICD 11	Status	REF
Hypertension	BA00-BA04	Approved	[1]

• Therapeutic Class: Antihypertensive Agents
• Cross-matching ID:
  PubChem CID: 38853
  ChEBI ID: CHEBI:61058
  CAS Number: 555-30-6
  TTD ID: D0BA6T
  VARIDT ID: DR00596
  INTEDE ID: DR1051
  ACDINA ID: D00417

Full List of Drug Formulations Containing This Drug

Methyldopa 250 mg tablet

Company	Formulation ID	FDA Description
Cardinal Health; Mylan Pharamceuticals	F13509	Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
Rebel Distributors	F13512	Citric acid; Magnesium stearate; Calcium sulfate; Edetate disodium; Talc; Titanium dioxide; Silicon dioxide; Ethylcellulose (10 mpa.s); Hydroxypropyl cellulose; Hypromelloses; Methylcellulose (15 cps); Polyethylene glycol; Sodium starch glycolate type a potato
Accord Healthcare	F13510	Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Povidone; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato; Starch, corn
Carilion Materials Management	F13511	Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Povidones; Sodium starch glycolate type a potato; Starch, corn
Physicians Total Care	F13505	Magnesium stearate; Calcium sulfate; Citric acid monohydrate; Edetate disodium; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Hydroxypropyl cellulose; Hypromelloses; Methylcellulose (400 cps); Polyethylene glycol; Sodium starch glycolate type a potato
Teva Pharmaceuticals	F13506	Magnesium stearate; Calcium sulfate; Citric acid monohydrate; Edetate disodium; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Hydroxypropyl cellulose (type h); Hypromellose 2910 (3 mpa.s); Methylcellulose (400 mpa.s); Polyethylene glycols; Sodium starch glycolate type a potato
Rebel Distributors	F13507	Magnesium stearate; Calcium sulfate; Citric acid monohydrate; Edetate disodium; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Hydroxypropyl cellulose (type h); Hypromelloses; Methylcellulose (400 mpa.s); Polyethylene glycols; Sodium starch glycolate type a potato
RemedyRepack	F13508	Magnesium stearate; Calcium sulfate; Citric acid monohydrate; Edetate disodium; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Hydroxypropyl cellulose; Hypromelloses; Methylcellulose (400 mpa.s); Polyethylene glycols; Sodium starch glycolate type a potato

Methyldopa 500 mg tablet

Company	Formulation ID	FDA Description
Mylan Pharamceuticals	F13515	Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
Rebel Distributors	F13518	Citric acid; Magnesium stearate; Edetate disodium; Titanium dioxide; Polysorbate 80; Silicon dioxide; Ethylcellulose (10 mpa.s); Hypromelloses; Methylcellulose (15 cps); Polyethylene glycol; Sodium starch glycolate type a potato
Accord Healthcare; Avera McKennan Hospital	F13516	Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Povidone; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
Bryant Ranch Prepack	F13517	Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Povidone, unspecified; Sodium starch glycolate type a potato
Physicians Total Care	F13514	Magnesium stearate; Citric acid monohydrate; Edetate disodium; Titanium dioxide; Polysorbate 80; Silicon dioxide; Ethylcelluloses; Hypromelloses; Methylcellulose (400 cps); Polyethylene glycol; Sodium starch glycolate type a potato
A-S Medication Solutions; Teva Pharmaceuticals	F13513	Magnesium stearate; Calcium sulfate; Citric acid monohydrate; Edetate disodium; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Hydroxypropyl cellulose (type h); Hypromellose 2910 (3 mpa.s); Methylcellulose (400 mpa.s); Polyethylene glycols; Sodium starch glycolate type a potato

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5217).