Details of the Drug Formulations

General Information of Drug (ID: DM5SYZP)

• Drug Name: Disopyramide Drug Info
• Synonyms: Dicorantil; Disopiramida; Disopyramidum; Isorythm; Lispine; Ritmodan; Rythmodan; Disopyramide Free Base; Rythmodan P; D 7644; H 3292; SC 7031; Searle 703; Disopiramida [INN-Spanish]; Disopyramidum [INN-Latin]; Norpace (TN); Rythmodan (TN); Rythmodan P (TN); Rythmodan-La; SC-7031; Xi-Disopyramide; Disopyramide (JP15/USAN/INN); Disopyramide [USAN:BAN:INN:JAN]; Alpha-Diisopropylaminoethyl-alpha-phenylpyridine-2-acetamide; Gamma-Diisopropylamino-alpha-phenyl-alpha-(2-pyridyl)butyramide; Alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide; Alpha-[2-[Bis(1-methylethyl)amino]ethyl]-alpha-phenyl-2-pyridine acetamide; 4-(diisopropylamino)-2-phenyl-2-pyridin-2-ylbutanamide; 4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide

Indication

Disease Entry	ICD 11	Status	REF
Long QT syndrome	BC65.0	Approved	[1]
Ventricular arrhythmias	BC71	Approved	[2]
Urinary incontinence	MF50.2	Withdrawn from market	[2]

• Therapeutic Class: Antiarrhythmic Agents
• Cross-matching ID:
  PubChem CID: 3114
  ChEBI ID: CHEBI:4657
  CAS Number: 3737-09-5
  TTD ID: D0M4YC
  VARIDT ID: DR00644
  INTEDE ID: DR0518
  ACDINA ID: D00205

Full List of Drug Formulations Containing This Drug

Disopyramide 100 mg capsule

Company	Formulation ID	FDA Description
Carilion Materials Management; Teva Pharmaceuticals	F06568	D&c red no. 28; Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; D&c red no. 33; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Sorbitan monolaurate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Aluminum oxide; Gelatin; Shellac; Sodium starch glycolate type a potato
AvKARE	F06569	D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; D&c red no. 33; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Propylene glycol; Titanium dioxide; Silicon dioxide; Aluminum oxide; Gelatin
Actavis Pharma	F06572	Methylparaben; D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Propylparaben; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Gelatin
G.D. Searle LLC Division of Pfizer Inc	F06571	Lactose, unspecified form; Fd&c yellow no. 6; Talc; Titanium dioxide; Fd&c red no. 3; Gelatin, unspecified; Starch, corn
G.D. Searle LLC Division of Pfizer Inc	F06567	Sucrose; Talc; Titanium dioxide; Ethylcellulose, unspecified; Starch, corn
Carilion Materials Management	F06570	Sucrose; Talc; Titanium dioxide; Ethylcelluloses; Starch, corn

Disopyramide 150 mg capsule

Company	Formulation ID	FDA Description
Teva Pharmaceuticals	F06574	D&c red no. 28; Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; D&c red no. 33; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Sorbitan monolaurate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Aluminum oxide; Gelatin; Shellac; Sodium starch glycolate type a potato
Carilion Materials Management	F06575	D&c red no. 28; Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; D&c red no. 33; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Sorbitan monolaurate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Aluminum oxide; Gelatin, unspecified; Shellac; Sodium starch glycolate type a potato
AvKARE	F06576	D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; D&c red no. 33; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Propylene glycol; Titanium dioxide; Silicon dioxide; Aluminum oxide; Gelatin
Actavis Pharma	F06579	Methylparaben; Sodium lauryl sulfate; Magnesium stearate; Propylparaben; Ferric oxide red; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Gelatin
G.D. Searle LLC Division of Pfizer Inc	F06573	Fd&c blue no. 1; Fd&c yellow no. 6; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Ethylcellulose, unspecified; Gelatin, unspecified; Shellac; Starch, corn
Carilion Materials Management	F06577	Fd&c blue no. 1; Fd&c yellow no. 6; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Ethylcelluloses; Gelatin; Shellac; Starch, corn
G.D. Searle LLC Division of Pfizer Inc	F06578	Lactose, unspecified form; Fd&c blue no. 1; Fd&c yellow no. 6; Talc; Titanium dioxide; Fd&c red no. 3; Gelatin, unspecified; Starch, corn

Disopyramide Phosphate eq 100mg base capsule

Company	Formulation ID	FDA Description
Teva Pharmaceuticals Usa	F23427	Lactose Monohydrate; Magnesium Stearate; Sodium Starch Glycolate; Black Iron Oxide; D&C Red 28; D&C Red 33; D&C Yellow 10; D&C Yellow 10 Aluminum Lake; Fd&C Blue 1; Fd&C Blue 1 Aluminum Lake; Fd&C Blue 2 Aluminum Lake; Fd&C Red 40 Aluminum Lake; Gelatin; Propylene Glycol; Shellac; Sodium Lauryl Sulfate; Sorbitan Monolaurate; Titanium Dioxide
Pfizer Laboratories Div Pfizer	F23423	Corn Starch; D&C Yellow No 10; Edible Ink; Ethylcellulose; Fd&C Blue No 1; Gelatin; Shellac; Sucrose; Talc; Titanium Dioxide
Pfizer Laboratories Div Pfizer	F23425	Corn Starch; Edible Ink; Fd&C Red No 3; Fd&C Yellow No 6; Gelatin; Lactose; Talc; Titanium Dioxide

Disopyramide Phosphate eq 150mg base capsule

Company	Formulation ID	FDA Description
Pfizer Laboratories Div Pfizer	F23424	Corn Starch; D&C Yellow No 10; Edible Ink; Ethylcellulose; Fd&C Blue No 1; Gelatin; Shellac; Sucrose; Talc; Titanium Dioxide; Fd&C Red No 3; Fd&C Yellow No 6
Pfizer Laboratories Div Pfizer	F23426	Corn Starch; Edible Ink; Fd&C Red No 3; Fd&C Yellow No 6; Gelatin; Lactose; Talc; Titanium Dioxide; Fd&C Blue No 1

References

• [1] Disopyramide FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7167).