Details of the Drug Formulations

General Information of Drug (ID: DM6F1PU)

Drug Name
Vortioxetine Drug Info
Synonyms
VORTIOXETINE; 508233-74-7; 1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine; Lu AA21004; UNII-3O2K1S3WQV; 3O2K1S3WQV; CHEBI:76016; Trintellix; 1-{2-[(2,4-dimethylphenyl)sulfanyl]phenyl}piperazine; Piperazine, 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-; Brintellix (TN); 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine; 1-[2-(2,4-dimethylphenyl)sulfanylphenyl]piperazine; 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]-piperazine; CHEMBL2204360; 1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine; Lu-AA21004
Indication
Disease Entry ICD 11 Status REF
Major depressive disorder 6A70.3 Approved [1]
Mood disorder 6A60-6E23 Phase 3 [2]
Cross-matching ID
PubChem CID
9966051
ChEBI ID
CHEBI:76016
CAS Number
508233-74-7
TTD ID
D03WEX
VARIDT ID
DR01102
INTEDE ID
DR1712
ACDINA ID
D00735

Full List of Drug Formulations Containing This Drug

Vortioxetine 15 mg tablet
Company Formulation ID FDA Description
Takeda Pharmaceuticals America F22502 Magnesium stearate; Mannitol; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a corn
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Vortioxetine 10 mg tablet
Company Formulation ID FDA Description
Avera McKennan Hospital; Takeda Pharmaceuticals America F22500 Magnesium stearate; Mannitol; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a corn
Avera McKennan Hospital; Takeda Pharmaceuticals America F22501 Magnesium stearate; Mannitol; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Hydroxypropyl cellulose (120000 mw); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Sodium starch glycolate type a potato
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Vortioxetine 20 mg tablet
Company Formulation ID FDA Description
Takeda Pharmaceuticals America F22503 Magnesium stearate; Mannitol; Ferric oxide red; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a corn
Takeda Pharmaceuticals America F22504 Magnesium stearate; Mannitol; Ferric oxide red; Titanium dioxide; Polyethylene glycol 400; Hydroxypropyl cellulose (120000 mw); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Sodium starch glycolate type a potato
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Vortioxetine 5 mg tablet
Company Formulation ID FDA Description
Takeda Pharmaceuticals America F22505 Magnesium stearate; Mannitol; Ferric oxide red; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a corn
Takeda Pharmaceuticals America F22506 Magnesium stearate; Mannitol; Ferric oxide red; Titanium dioxide; Polyethylene glycol 400; Hydroxypropyl cellulose (120000 mw); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Sodium starch glycolate type a potato
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Vortioxetine Hydrobromide eq 15mg base tablet
Company Formulation ID FDA Description
Takeda Pharms Usa F23600 Mannitol; Microcrystalline Cellulose; Hydroxypropyl Cellulose; Sodium Starch Glycolate; Magnesium Stearate; Hypromellose; Titanium Dioxide; Polyethylene Glycol 400; Iron Oxide Yellow; Iron Oxide Red
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Vortioxetine Hydrobromide eq 10mg base tablet
Company Formulation ID FDA Description
Takeda Pharms Usa F23599 Mannitol; Microcrystalline Cellulose; Hydroxypropyl Cellulose; Sodium Starch Glycolate; Magnesium Stearate; Hypromellose; Titanium Dioxide; Polyethylene Glycol 400; Iron Oxide Yellow
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Vortioxetine Hydrobromide eq 5mg base tablet
Company Formulation ID FDA Description
Takeda Pharms Usa F24005 Mannitol; Microcrystalline Cellulose; Hydroxypropyl Cellulose; Sodium Starch Glycolate; Magnesium Stearate; Hypromellose; Titanium Dioxide; Polyethylene Glycol 400; Iron Oxide Red
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Vortioxetine Hydrobromide eq 20mg base tablet
Company Formulation ID FDA Description
Takeda Pharms Usa F24006 Mannitol; Microcrystalline Cellulose; Hydroxypropyl Cellulose; Sodium Starch Glycolate; Magnesium Stearate; Hypromellose; Titanium Dioxide; Polyethylene Glycol 400; Iron Oxide Red
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7351).
2 Vortioxetine (Lu AA21004), a novel multimodal antidepressant, enhances memory in rats. Pharmacol Biochem Behav. 2013 Apr;105:41-50.