Details of the Drug Formulations

General Information of Drug (ID: DM7HXWT)

Drug Name
Nilotinib Drug Info
Synonyms
NIL; Nilotinibum; Tasigna (Novartis); Nilotinib (INN/USAN); Nilotinib, AMN107, Tasigna; Tasigna, AMN-107, Nilotinib; L-1-yl)-3-(trifluoromethyl)phenyl]benzamide; Benzamide, 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-(9CI); 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazo; 4-Methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide; 4-Methyl-N-[3-(4-methylimidazol-1-yl)-5-trifluoromethylphenyl]-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzamide; 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide; Nilotinib (BCR-ABL inhibitor 2nd gen)
Indication
Disease Entry ICD 11 Status REF
Chronic myelogenous leukaemia 2A20.0 Approved [1]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
644241
ChEBI ID
CHEBI:52172
CAS Number
641571-10-0
TTD ID
D00STL
VARIDT ID
DR00013
INTEDE ID
DR1155
ACDINA ID
D00468

Full List of Drug Formulations Containing This Drug

Nilotinib Hydrochloride Monohydrate eq 50mg base capsule
Company Formulation ID FDA Description
Novartis F23493 Colloidal Silicon Dioxide; Crospovidone; Lactose Monohydrate; Magnesium Stearate; Poloxamer 188; Gelatin; Iron Oxide (Red); Iron Oxide (Yellow); Iron Oxide (Black); Titanium Dioxide
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Nilotinib Hydrochloride Monohydrate eq 150mg base capsule
Company Formulation ID FDA Description
Novartis F23975 Colloidal Silicon Dioxide; Crospovidone; Lactose Monohydrate; Magnesium Stearate; Poloxamer 188; Gelatin; Iron Oxide (Red); Iron Oxide (Yellow); Iron Oxide (Black)=; Titanium Dioxide
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Nilotinib Hydrochloride Monohydrate eq 200mg base capsule
Company Formulation ID FDA Description
Novartis F23976 Colloidal Silicon Dioxide; Crospovidone; Lactose Monohydrate; Magnesium Stearate; Poloxamer 188; Gelatin; Iron Oxide (Red); Iron Oxide (Yellow); Iron Oxide (Black)=; Titanium Dioxide
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Nilotinib 150 mg capsule
Company Formulation ID FDA Description
Novartis Pharmaceuticals Corporation F15371 Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Crospovidone; Poloxamer 188; Silicon dioxide; Gelatin
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Nilotinib 200 mg capsule
Company Formulation ID FDA Description
Novartis Pharmaceuticals Corporation F15372 Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Crospovidone; Poloxamer 188; Silicon dioxide; Gelatin
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5697).