Details of the Drug Formulations

General Information of Drug (ID: DM8QB1D)

• Drug Name: Olaparib Drug Info
• Synonyms: AZD 2281; AZD2281; AZD-2281; Acylpiperazine analogue, 47; KU-0059436; KU-59436; Olaparib, KU-0059436, AZD2281,KU0059436, AZD2281; 4-[(3-{[4-Cyclopropylcarbonyl)piperazin-4-yl]carbonyl}-4-fluorophenyl)methyl]phtalazin-1(2H)-one; 4-[3-(4-Cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one

Indication

Disease Entry	ICD 11	Status	REF
Ovarian cancer	2C73	Approved	[1]
Pancreatic cancer	2C10	Phase 3	[2]
Prostate cancer	2C82.0	Phase 3	[2]

• Cross-matching ID:
  PubChem CID: 23725625
  ChEBI ID: CHEBI:83766
  CAS Number: 763113-22-0
  TTD ID: D0J9HW
  VARIDT ID: DR00221
  INTEDE ID: DR1188
  ACDINA ID: D00485

Full List of Drug Formulations Containing This Drug

Olaparib 100 mg tablet

Company	Formulation ID	FDA Description
AstraZeneca	F15761	Sodium stearyl fumarate; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Water; Polyethylene glycol 400; Silicon dioxide; Copovidone k25-31; Hypromelloses

Olaparib 150 mg tablet

Company	Formulation ID	FDA Description
AstraZeneca	F15762	Sodium stearyl fumarate; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Water; Polyethylene glycol 400; Silicon dioxide; Copovidone k25-31; Hypromelloses

Olaparib 50 mg capsule

Company	Formulation ID	FDA Description
AstraZeneca	F15763	Potassium acetate; Butyl alcohol; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Gellan gum (low acyl); Hypromelloses; Lauroyl peg-32 glycerides; Shellac

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7519).
• [2] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)