Details of the Drug Formulations

General Information of Drug (ID: DMA16BR)

• Drug Name: Vorapaxar Drug Info
• Synonyms: Vorapaxar; 618385-01-6; Zontivity; SCH-530348; SCH530348; UNII-ZCE93644N2; CHEMBL493982; CHEBI:82702; ZCE93644N2; MK-5348; ethyl ((1R,3aR,4aR,6R,8aR,9S,9aS)-9-((E)-2-(5-(3-fluorophenyl)pyridin-2-yl)vinyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl)carbamate; Ethyl [(1r,3ar,4ar,6r,8ar,9s,9as)-9-{(E)-2-[5-(3-Fluorophenyl)pyridin-2-Yl]ethenyl}-1-Methyl-3-Oxododecahydronaphtho[2,3-C]furan-6-Yl]carbamate; Vorapaxar [USAN:INN]; Carbamic acid, [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2- pyridinyl]etheny

Indication

Disease Entry	ICD 11	Status	REF
Myocardial infarction	BA41-BA43	Approved	[1]
Stroke	8B20	Investigative	[2]

• Cross-matching ID:
  PubChem CID: 10077130
  ChEBI ID: CHEBI:82702
  CAS Number: 618385-01-6
  TTD ID: D0VA0I
  INTEDE ID: DR1708
  ACDINA ID: D00732

Full List of Drug Formulations Containing This Drug

Vorapaxar Sulfate eq 2.08mg base tablet

Company	Formulation ID	FDA Description
Xspire Pharma	F23357	Lactose Monohydrate; Microcrystalline Cellulose; Croscarmellose Sodium; Povidone; Magnesium Stearate; Lactose Monohydrate; Hypromellose; Titanium Dioxide; Triacetin (Glycerol Triacetate); Iron Oxide Yellow

Vorapaxar 2.08 mg tablet

Company	Formulation ID	FDA Description
Aralez Pharmaceuticals; Merck Sharp & Dohme	F22463	Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Hypromellose 2910 (15 mpa.s); Povidones

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4047).
• [2] Vorapaxar FDA Label