Details of the Drug Formulations

General Information of Drug (ID: DMB920Z)

• Drug Name: Ceritinib Drug Info
• Synonyms: ceritinib; LDK378; 1032900-25-6; ZYKADIA; NVP-LDK378-NX; LDK-378; UNII-K418KG2GET; LDK378(Ceritinib); LDK 378; Eritinib (LDK378); 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine; K418KG2GET; CHEMBL2403108; CHEBI:78432; AK174337; ceritinib; C28H36ClN5O3S; 5-Chloro-N2-[2-isopropoxy-5-Methyl-4-(4-piperidyl)phenyl]-N4-(2-isopropylsulfonylphenyl)pyriMidine-2,4-diaMine; 5-Chloro-N2-(5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl)-N4-(2-(propane-2-sulfonyl)phenyl)pyrim

Indication

Disease Entry	ICD 11	Status	REF
Non-small-cell lung cancer	2C25.Y	Approved	[1]

• Cross-matching ID:
  PubChem CID: 57379345
  ChEBI ID: CHEBI:78432
  CAS Number: 1032900-25-6
  TTD ID: D04LVK
  VARIDT ID: DR00228
  ACDINA ID: D00115

Full List of Drug Formulations Containing This Drug

Ceritinib 150 mg capsule

Company	Formulation ID	FDA Description
Novartis Pharmaceuticals Corporation	F03862	Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Hydroxypropyl cellulose (type h); Sodium starch glycolate type a potato

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7397).