Details of the Drug Formulations

General Information of Drug (ID: DMCMBHA)

• Drug Name: Erlotinib Drug Info
• Synonyms: Erlotinin; Tarceva; Erlotinib Base; OSI 744; R 1415; CP 358,774; CP-358774; Erlotinib(Tarceva); Tarceva (TN); CP-358,774; Erlotinib, OS-774; N-(3-ethynylphenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine; N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine; N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine; N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-Quinazolinamine; [6,7-BIS(2-METHOXY-ETHOXY)QUINAZOLINE-4-YL]-(3-ETHYNYLPHENYL)AMINE; [6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine; 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline; 4-[(3-ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline

Indication

Disease Entry	ICD 11	Status	REF
Adrenal gland neoplasm		Approved	[1]
Adult hepatocellular carcinoma		Approved	[1]
Brain cancer	2A00	Approved	[1]
Esophageal disorder		Approved	[1]
Lung cancer	2C25.0	Approved	[1]
Non-small-cell lung cancer	2C25.Y	Approved	[2]
Pancreatic adenocarcinoma		Approved	[1]
Psoriasis	EA90	Approved	[1]
Salivary gland squamous cell carcinoma		Approved	[1]
Pancreatic cancer	2C10	Phase 3	[2]
Colon cancer	2B90.Z	Phase 2	[2]
Ependymoma	2A00.0Y	Investigative	[1]
Neoplastic meningitis		Investigative	[1]
Neuroblastoma	2D11.2	Investigative	[1]

• Therapeutic Class: Anticancer Agents
• Cross-matching ID:
  PubChem CID: 176870
  ChEBI ID: CHEBI:114785
  CAS Number: 183321-74-6
  TTD ID: D07POC
  VARIDT ID: DR00558
  INTEDE ID: DR0603
  ACDINA ID: D00239

Full List of Drug Formulations Containing This Drug

Erlotinib 25 mg tablet

Company	Formulation ID	FDA Description
Physicians Total Care	F07350	Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Sodium starch glycolate type a potato

Erlotinib 100 mg tablet

Company	Formulation ID	FDA Description
Physicians Total Care	F07348	Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Sodium starch glycolate type a potato

Erlotinib 150 mg tablet

Company	Formulation ID	FDA Description
Physicians Total Care	F07349	Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Sodium starch glycolate type a potato

References

• [1] Erlotinib FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4920).