General Information of Drug (ID: DMD1QXW)

Drug Name
Ambrisentan Drug Info
Synonyms
Letairis; Ambrisentan [INN]; Gilead brand of ambrisentan; BSF 208075; BSF208075; LU 208075; LU208075; BSF-208075; LU-208075; Benzenepropanoic acid, .alpha.-[(4,6-dimethyl-2-pyrimidinyl)oxy]-.beta.-methoxy-.beta.-phe; (+-)-(2S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid; 2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenyl-propanoic acid; 2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid; 2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid
Indication
Disease Entry ICD 11 Status REF
Pulmonary arterial hypertension BB01.0 Approved [1]
Cross-matching ID
PubChem CID
6918493
ChEBI ID
CHEBI:135949
CAS Number
177036-94-1
TTD ID
D0X5ZI
VARIDT ID
DR00311
INTEDE ID
DR0080
ACDINA ID
D00028

Full List of Drug Formulations Containing This Drug

Ambrisentan 10 mg tablet
Company Formulation ID FDA Description
Gilead Sciences F00943 Lactose monohydrate; Fd&c red no. 40; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Polyethylene glycol 3350; Polyvinyl alcohol; Aluminum oxide; Cellulose, microcrystalline
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Ambrisentan 5 mg tablet
Company Formulation ID FDA Description
Gilead Sciences F00944 Lactose monohydrate; Fd&c red no. 40; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Polyethylene glycol 3350; Polyvinyl alcohol; Aluminum oxide; Cellulose, microcrystalline
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3951).