Details of the Drug Formulations

General Information of Drug (ID: DMD7L94)

Drug Name
Palbociclib Drug Info
Synonyms
571190-30-2; PD0332991; PD-0332991; Ibrance; PD 0332991; UNII-G9ZF61LE7G; Palbociclib(PD0332991); 6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(piperazin-1-yl)pyridin-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one; 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one; G9ZF61LE7G; PD 332991; 6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-[(5-PIPERAZIN-1-YLPYRIDIN-2-YL)AMINO]PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE; LQQ; PD 332991, PD 0332991, PD0332991; 6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-ylpyridin-2-ylamino)-8H-pyrido(2,3-d)pyrimidin-7-one; 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one; HMR-2934
Indication
Disease Entry ICD 11 Status REF
Breast cancer 2C60-2C65 Approved [1]
Solid tumour/cancer 2A00-2F9Z Phase 2 [2] , [3]
Schizophrenia 6A20 Terminated [4]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
5330286
ChEBI ID
CHEBI:85993
CAS Number
571190-30-2
TTD ID
D00UZR
VARIDT ID
DR01288
INTEDE ID
DR1229
ACDINA ID
D00504

Full List of Drug Formulations Containing This Drug

Palbociclib 100 mg capsule
Company Formulation ID FDA Description
Pfizer Laboratories F16452 Lactose monohydrate; Magnesium stearate; Ammonia; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Silicon dioxide; Dimethicone; Gelatin, unspecified; Microcrystalline cellulose; Shellac; Sodium starch glycolate type a potato
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Palbociclib 125 mg capsule
Company Formulation ID FDA Description
U.S. Pharmaceuticals F16453 Lactose monohydrate; Magnesium stearate; Ammonia; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Dimethicone; Gelatin; Shellac; Sodium starch glycolate type a potato
Pfizer Laboratories F16454 Lactose monohydrate; Magnesium stearate; Ammonia; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Silicon dioxide; Dimethicone; Gelatin, unspecified; Microcrystalline cellulose; Shellac; Sodium starch glycolate type a potato
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Palbociclib 75 mg capsule
Company Formulation ID FDA Description
Pfizer Laboratories F16455 Lactose monohydrate; Magnesium stearate; Ammonia; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Silicon dioxide; Dimethicone; Gelatin, unspecified; Microcrystalline cellulose; Shellac; Sodium starch glycolate type a potato
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References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2017
2 ClinicalTrials.gov (NCT01723774) PD 0332991 and Anastrozole for Stage 2 or 3 Estrogen Receptor Positive and HER2 Negative Breast Cancer. U.S. National Institutes of Health.
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4 The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22.