General Information of Drug (ID: DMDI269)

Drug Name
Docetaxel Drug Info
Synonyms
EmDOC; TXL; Taxotere; Docetaxel anhydrous; ANX-514; Docetaxel (INN); Docetaxel, Trihydrate; RP-56976; SDP-014; Taxotere (TN); Taxotere(R); XRP-6976L; Docetaxel 114977-28-5; N-debenzoyl-N-Boc-10-deacetyl taxol; N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel; N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol; (2alpha,5beta,7beta,10beta,13alpha)-4-(acetyloxy)-13-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate; 4-(acetyloxy)-13alpha-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7beta,10beta-trihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate
Indication
Disease Entry ICD 11 Status REF
Advanced cancer 2A00-2F9Z Approved [1]
Breast carcinoma Approved [1]
Head and neck cancer 2D42 Approved [1]
Leiomyosarcoma 2B58 Approved [1]
Lung cancer 2C25.0 Approved [1]
Non-small-cell lung cancer 2C25.Y Approved [1]
Prostate adenocarcinoma Approved [1]
Prostate cancer 2C82.0 Approved [1]
Solid tumour/cancer 2A00-2F9Z Approved [2]
Urinary system neoplasm Approved [1]
Gastric cancer 2B72 Investigative [1]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
148124
ChEBI ID
CHEBI:4672
CAS Number
114977-28-5
TTD ID
D0O5WP
VARIDT ID
DR00251
INTEDE ID
DR0520
ACDINA ID
D01011

Full List of Drug Formulations Containing This Drug

Docetaxel 20mg/2ml injectable
Company Formulation ID FDA Description
F23718 Polysorbate 80; Citric Acid Monohydrate; Dehydrated Alcohol
------------------------------------------------------------------------------------
Docetaxel 80mg/4ml injectable
Company Formulation ID FDA Description
Sanofi Aventis Us F24187 Polysorbate 80; Dehydrated Alcohol Solution
------------------------------------------------------------------------------------
Docetaxel 160mg/8ml injectable
Company Formulation ID FDA Description
Jiangsu Hengrui Medicine Co. Ltd. F24188 Polysorbate 80; Dehydrated Alcohol Solution
------------------------------------------------------------------------------------

References

1 Docetaxel FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6809).