Details of the Drug Formulations

General Information of Drug (ID: DMEXMYK)

Drug Name
Alpelisib Drug Info
Synonyms
alpelisib; 1217486-61-7; BYL-719; BYL719; UNII-08W5N2C97Q; BYL 719; Alpelisib (BYL719); (S)-N1-(4-Methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-yl)pyrrolidine-1,2-dicarboxamide; NVP-BYL719; (2S)-N1-[4-Methyl-5-[2-(2,2,2-trifluoro-1,1-dimethylethyl)-4-pyridinyl]-2-thiazolyl]-1,2-pyrrolidinedicarboxamide; CHEMBL2396661; 08W5N2C97Q; AK146107; C19H22F3N5O2S; (S)-N1-(4-Methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)-pyridin-4-yl)thiazol-2-yl)pyrrolidine-1,2-dicarboxamide
Indication
Disease Entry ICD 11 Status REF
Breast cancer 2C60-2C65 Approved [1]
Solid tumour/cancer 2A00-2F9Z Phase 2 [2]
Cross-matching ID
PubChem CID
56649450
ChEBI ID
CHEBI:93752
CAS Number
1217486-61-7
TTD ID
D0W7HE
INTEDE ID
DR0074
ACDINA ID
D00827

Full List of Drug Formulations Containing This Drug

Alpelisib 50mg tablet
Company Formulation ID FDA Description
Novartis F24013 Hypromellose; Magnesium Stearate; Mannitol; Microcrystalline Cellulose; Sodium Starch Glycolate; Hypromellose; Iron Oxide Black; Iron Oxide Red; Macrogol/Polyethylene Glycol (Peg) 4000; Talc; Titanium Dioxide
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Alpelisib 150mg tablet
Company Formulation ID FDA Description
Novartis F24014 Hypromellose; Magnesium Stearate; Mannitol; Microcrystalline Cellulose; Sodium Starch Glycolate; Hypromellose; Iron Oxide Black; Iron Oxide Red; Macrogol/Polyethylene Glycol (Peg) 4000; Talc; Titanium Dioxide
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Alpelisib 200mg tablet
Company Formulation ID FDA Description
Novartis F24015 Hypromellose; Magnesium Stearate; Mannitol; Microcrystalline Cellulose; Sodium Starch Glycolate; Hypromellose; Iron Oxide Black; Iron Oxide Red; Macrogol/Polyethylene Glycol (Peg) 4000; Talc; Titanium Dioxide
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References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2019
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7955).