Details of the Drug Formulations

General Information of Drug (ID: DMHSY1I)

• Drug Name: Regorafenib Drug Info
• Synonyms: Regorafenib; 755037-03-7; BAY 73-4506; Regorafenibum; Stivarga; 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide; BAY73-4506; Regorafenib (BAY 73-4506); UNII-24T2A1DOYB; 4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide; BAY-73-4506; 24T2A1DOYB; CHEMBL1946170; CHEBI:68647; Stivarga (TN); BAY73-4506 hydrochloride; Regorafenib [USAN:INN]

Indication

Disease Entry	ICD 11	Status	REF
Gastrointestinal stromal tumour	2B5B	Approved	[1]
Metastasis from malignant tumor of colon		Approved	[1]
Metastatic colorectal cancer	2B91	Approved	[2]

• Cross-matching ID:
  PubChem CID: 11167602
  ChEBI ID: CHEBI:68647
  CAS Number: 755037-03-7
  TTD ID: D09GDD
  VARIDT ID: DR00136
  INTEDE ID: DR1401
  ACDINA ID: D00586

Full List of Drug Formulations Containing This Drug

Regorafenib 40 mg tablet

Company	Formulation ID	FDA Description
Bayer HealthCare	F18895	Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Polyethylene glycol 3350; Silicon dioxide; Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Povidone, unspecified

References

• [1] Regorafenib FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5891).