Details of the Drug Formulations

General Information of Drug (ID: DMIOGBU)

Drug Name
Bosentan Drug Info
Synonyms
Actelion; Bosentanum; Tracleer; Bosentan (INN); KS-5062; Ro 47-0203; Tracleer (TN); Bosentan [USAN:INN:BAN]; Ro 47-0203/039; Ro-47-0203; Ro-47-0203/029; Ro-47-0203/039; P-tert-Butyl-N-[6-(2-hydroxyethoxy); P-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide; 4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide; 4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl)benzenesulfornamide; 4-t-butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide; 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide; 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
Indication
Disease Entry ICD 11 Status REF
Pulmonary arterial hypertension BB01.0 Approved [1]
Pulmonary hypertension BB01 Approved [2]
Scleroderma 4A42 Investigative [2]
Therapeutic Class
Antihypertensive Agents
Cross-matching ID
PubChem CID
104865
ChEBI ID
CHEBI:51450
CAS Number
147536-97-8
TTD ID
D0U4CE
VARIDT ID
DR00288
INTEDE ID
DR0222
ACDINA ID
D00074

Full List of Drug Formulations Containing This Drug

Bosentan 32 mg tablet
Company Formulation ID FDA Description
Actelion Pharmaceuticals US F02697 Phenylalanine; Acesulfame potassium; Aspartame; Magnesium stearate; Tartaric acid; Anhydrous dibasic calcium phosphate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
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Bosentan 125 mg tablet
Company Formulation ID FDA Description
Actelion Pharmaceuticals US F02696 Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Ethylcellulose, unspecified; Hypromellose, unspecified; Povidone k90; Sodium starch glycolate type a potato; Starch, corn
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Bosentan 62.5 mg tablet
Company Formulation ID FDA Description
Actelion Pharmaceuticals US F02698 Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Ethylcellulose, unspecified; Hypromellose, unspecified; Povidone k90; Sodium starch glycolate type a potato; Starch, corn
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3494).
2 Bosentan FDA Label