Details of the Drug Formulations

General Information of Drug (ID: DMIWFRL)

• Drug Name: Tolvaptan Drug Info
• Synonyms: Samsca; OPC 41061; Benzazepine derivative, 32; OPC-41061; Samsca (TN); N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-methylbenzamide; (-)-4'-((7-Chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl)-o-tolu-m-toluidide; 7-Chloro-5-hydroxy-1-(2-methyl-4-(2-methylbenzoylamino)benzoyl)2,3,4,5-tetrahydro-1H-1-benzazepine

Indication

Disease Entry	ICD 11	Status	REF
Autosomal dominant polycystic kidney disease	GB81	Approved	[1]
Hyponatraemia	5C72	Approved	[2]
Heart failure	BD10-BD13	Phase 3	[2]
Hypernatremia	5C71	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 216237
  ChEBI ID: CHEBI:32246
  CAS Number: 150683-30-0
  TTD ID: D03KZM
  VARIDT ID: DR00059
  INTEDE ID: DR1617
  ACDINA ID: D00688

Full List of Drug Formulations Containing This Drug

Tolvaptan 15 mg tablet

Company	Formulation ID	FDA Description
Otsuka America Pharmaceutical	F21204	Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Aluminum oxide; Hydroxypropyl cellulose (1200000 mw); Low-substituted hydroxypropyl cellulose, unspecified; Microcrystalline cellulose; Starch, corn

References

• [1] Tolvaptan FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2226).