Details of the Drug Formulations

General Information of Drug (ID: DMJ0QOW)

• Drug Name: Rilpivirine Drug Info
• Synonyms: 500287-72-9; TMC278; Edurant; TMC 278; UNII-FI96A8X663; R278474; TMC-278; 4-{[4-({4-[(E)-2-Cyanoethenyl]-2,6-Dimethylphenyl}amino)pyrimidin-2-Yl]amino}benzonitrile; CHEBI:68606; FI96A8X663; R 278474; 4-{[4-({4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile; (E)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile; (E)-4-(4-(4-(2-cyanovinyl)-2,6-dimethylphenylamino)pyrimidin-2-ylamino)benzonitrile; W-202888; RPV; Mu O-conotoxin

Indication

Disease Entry	ICD 11	Status	REF
Human immunodeficiency virus infection	1C62	Approved	[1]
Pain	MG30-MG3Z	Investigative	[2]

• Cross-matching ID:
  PubChem CID: 6451164
  ChEBI ID: CHEBI:68606
  CAS Number: 500287-72-9
  TTD ID: D0T6WN
  INTEDE ID: DR1424
  ACDINA ID: D00594

Full List of Drug Formulations Containing This Drug

Rilpivirine 25 mg tablet

Company	Formulation ID	FDA Description
Janssen Products	F18996	Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Polysorbate 20; Povidone k30; Silicon dioxide; Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Polyethylene glycol 3000

Rilpivirine Hydrochloride eq 25mg base tablet

Company	Formulation ID	FDA Description
Janssen Prods	F23336	Croscarmellose Sodium, Lactose Monohydrate, Magnesium Stearate, Polysorbate 20, Povidone K30; Silicified Microcrystalline Cellulose; Hypromellose 2910 6 Mpa.S; Lactose Monohydrate; Peg 3000; Titanium Dioxide; Triacetin

References

• [1] 2011 FDA drug approvals. Nat Rev Drug Discov. 2012 Feb 1;11(2):91-4.
• [2] Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian senso... J Biol Chem. 2004 Jun 11;279(24):25774-82.