General Information of Drug (ID: DMK1CZJ)

Drug Name
Ingenol mebutate Drug Info
Synonyms
Picato; Ingenol 3-angelate; 75567-37-2; PEP-005; PEP005; 3-Angeloylingenol; UNII-7686S50JAH; PEP 005; 3-Ingenyl angelate; Ingenol-3-angelate; 7686S50JAH; Picato (TN); Euphorbia factor H1; Euphorbia factor An1; Ingenol mebutate [USAN:INN]; [dihydroxy-(hydroxymethyl)-tetramethyl-oxo-[ ]yl] (Z)-2-methylbut-2-enoate; I3A; Ingenol-3- angelate; Ingenol mebutate (USAN); (Z)-2-methylbut-2-enoate; SCHEMBL2526605; GTPL7443; CHEMBL1863513; HSDB 8308; VDJHFHXMUKFKET-WDUFCVPESA-N; MolPort-003-941-761; AN-262; POL-103A
Indication
Disease Entry ICD 11 Status REF
Actinic keratosis EK90.0 Approved [1]
Melanoma 2C30 Phase 3 [2]
Cross-matching ID
PubChem CID
6918670
ChEBI ID
CHEBI:66913
CAS Number
75567-37-2
TTD ID
D0E9KA
VARIDT ID
DR01483
ACDINA ID
D01160

Full List of Drug Formulations Containing This Drug

Ingenol Mebutate 0.015% gel
Company Formulation ID FDA Description
Leo Labs F24066 Isopropyl Alcohol; Hydroxyethyl Cellulose; Citric Acid Monohydrate; Sodium Citrate; Benzyl Alcohol; Purified Water
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Ingenol Mebutate 0.05% gel
Company Formulation ID FDA Description
Leo Labs F24067 Isopropyl Alcohol; Hydroxyethyl Cellulose; Citric Acid Monohydrate; Sodium Citrate; Benzyl Alcohol; Purified Water
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7443).
2 ClinicalTrials.gov (NCT01546571) Study of a Melanoma Vaccine in Stage IIb, IIc, and III Melanoma Patients. U.S. National Institutes of Health.