Details of the Drug Formulations

General Information of Drug (ID: DMLBVKQ)

• Drug Name: Entacapone Drug Info
• Synonyms: Comtan; Comtess; Entacapona; Entacaponum; Novartis brand of entacapone; Orion brand of entacapone; KB475572; OR 611; COM-998; Comtan (TN); Entacapona [INN-Spanish]; Entacapone [USAN:INN]; Entacaponum [INN-Latin]; OR-611; Stalevo (TN); Entacapone (JAN/USAN/INN); N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl) acrylamide; (2E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide; (E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide; (E)-2-cyano-3-(3,4-dihydroxy-5-nitro-phenyl)-N,N-diethyl-prop-2-enamide; (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide; (E)-alpha-Cyano-N,N-diethyl-3,4-dihydroxy-5-nitrocinnamamide; 2-Cyano-N,N-diethyl-3-(3,4-dihydroxy-5-nitrophenyl)propenamide

Indication

Disease Entry	ICD 11	Status	REF
Parkinson disease	8A00.0	Approved	[1]

• Therapeutic Class: Antiparkinson Agents
• Cross-matching ID:
  PubChem CID: 5281081
  ChEBI ID: CHEBI:4798
  CAS Number: 130929-57-6
  TTD ID: D0J1VY
  VARIDT ID: DR01275
  INTEDE ID: DR0581
  ACDINA ID: D00231

Full List of Drug Formulations Containing This Drug

Entacapone 200 mg tablet

Company	Formulation ID	FDA Description
Wockhardt	F07283	D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a potato
Mylan Pharamceuticals	F07285	Sucralose; Magnesium stearate; Mannitol; Ferric oxide red; Ferric oxide yellow; Glycerin; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hypromelloses
Aurobindo Pharma; AvPAK; Avera McKennan Hospital	F07290	Lactose monohydrate; Magnesium stearate; Mannitol; Ferric oxide red; Ferric oxide yellow; Glycerin; Sucrose; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a potato
American Health Packaging	F07291	Lactose monohydrate; Magnesium stearate; Mannitol; Ferric oxide red; Ferric oxide yellow; Glycerin; Sucrose; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Hydrogenated cottonseed oil; Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Sodium starch glycolate type a potato
Aphena Pharma Solutions-Tennessee; Wockhardt	F07284	Magnesium stearate; Mannitol; Ferric oxide red; Ferric oxide yellow; Glycerin; Sucrose; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hypromelloses
AvKARE; Avera McKennan Hospital; Mylan Pharamceuticals; Sun Pharmaceutical Industries	F07286	Magnesium stearate; Mannitol; Ferric oxide red; Ferric oxide yellow; Glycerin; Sucrose; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hypromelloses
Cardinal Health	F07289	Magnesium stearate; Mannitol; Ferric oxide red; Ferric oxide yellow; Glycerin; Sucrose; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hydroxypropyl cellulose
Novartis Pharmaceuticals Corporation	F07292	Magnesium stearate; Mannitol; Ferric oxide red; Ferric oxide yellow; Glycerin; Sucrose; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Hydrogenated cottonseed oil; Hypromellose, unspecified; Microcrystalline cellulose
Kaiser Foundation Hospitals; Sandoz	F07293	Magnesium stearate; Mannitol; Ferric oxide red; Ferric oxide yellow; Glycerin; Sucrose; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hypromelloses
Sun Pharmaceutical Industries	F07287	Magnesium stearate; Mannitol; Ferric oxide red; Ferric oxide yellow; Glycerin; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s)
Macleods Pharmaceuticals	F07288	Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Croscarmellose sodium; Povidone; Cellulose, microcrystalline; Hypromelloses; Starch, corn
Ajanta Pharmaceutical	F07294	Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Water; Polyoxyl 40 hydrogenated castor oil; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6647).