Details of the Drug Formulations

General Information of Drug (ID: DMP79A1)

• Drug Name: Macitentan Drug Info
• Synonyms: Macitentan; 441798-33-0; Opsumit; ACT-064992; ACT 064992; UNII-Z9K9Y9WMVL; ACT064992; Z9K9Y9WMVL; N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propylsulfamide; N-(5-(4-Bromophenyl)-6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-4-pyrimidinyl)-N'-propylsulfamide; CHEBI:76607; Actelion-1; Macitentan [USAN:INN]; macitentanum; zlchem 5; Opsumit (TN); Macitentan (JAN/USAN); (non-labelled)Macitentan-d7; MLS006011174; C19H20Br2N6O4S; SCHEMBL1445625; GTPL7352; CHEMBL2103873; ZLA0005; EX-A544; DTXSID50196063

Indication

Disease Entry	ICD 11	Status	REF
Cardiovascular disease	BA00-BE2Z	Approved	[1]

• Cross-matching ID:
  PubChem CID: 16004692
  ChEBI ID: CHEBI:76607
  CAS Number: 441798-33-0
  TTD ID: D0S7JH
  INTEDE ID: DR0998
  ACDINA ID: D00382

Full List of Drug Formulations Containing This Drug

Macitentan 10 mg tablet

Company	Formulation ID	FDA Description
Actelion Pharmaceuticals US	F12695	Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Lecithin, soybean; Polysorbate 80; Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Povidone, unspecified; Sodium starch glycolate type a potato; Xanthan gum

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7352).