Details of the Drug Formulations

General Information of Drug (ID: DMPRI8G)

Drug Name
Buprenorphine Drug Info
Synonyms
Buprel; Buprenex; Buprenophine; Buprenorfina; Buprenorphinum; Probuphine; Temgesic; Buprenorphine Hcl; RX 6029M; Buprenex (TN); Buprenorfina [INN-Spanish]; Buprenorphine [INN:BAN]; Buprenorphinum [INN-Latin]; Subutex (TN); Temgesic (TN); Buprenorphine (JAN/INN); RX-6029-M; Suboxone (TN); [5alpha,7alpha(S)]-17-(Cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-6,14-ethenomorphinan-7-methanol; (-)-buprenorphine; (5alpha,6beta,14beta,18R)-17-(cyclopropylmethyl)-18-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-(methyloxy)-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol; (5alpha,6beta,14beta,18R)-17-(cyclopropylmethyl)-18-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-6-methoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol; 17-Cyclopropylmethyl-4,5alpha-epoxy-7alpha-((S)-1-hydroxy-1,2,2-trimethylpropyl-6-methoxy-6,14-endo-ethanomorphinan-3-ol; 17-cyclopropylmethyl-4,5alpha-epoxy-7alpha-((S)-1-hydroxy-1,2,2-trimethylpropyl)-6-methoxy-6,14-endo-ethanomorphinan-3-ol; 2-(N-Cyclopropylmethyl-4,5alpha-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-7alpha-yl)-3,3-dimethyl-2-butanol; 2-(N-cyclopropylmethyl-4,5alpha-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6alpha-yl)-3,3-dimethyl-2-butanol; 21-(Cyclopropyl-7alpha-((S)-1-hydroxy-1,2,2-trimethylpropyl-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine; 21-cyclopropyl-7alpha-(2-hydroxy-3,3-dimethyl-2-butyl)-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine; 21-cyclopropyl-7alpha-[(S)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine; 6,14-Ethenomorphinan-7-methanol; 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-, (alphaS,5alpha,7alpha)-(9CI); 6029-M
Indication
Disease Entry ICD 11 Status REF
Opioid dependence 6C43.2Z Approved [1]
Pain MG30-MG3Z Approved [2]
Psychiatric disorder 6E8Z Phase 3 [3]
Migraine 8A80 Phase 2 [4]
Chronic pain MG30 Investigative [1]
Therapeutic Class
Analgesics
Cross-matching ID
PubChem CID
644073
ChEBI ID
CHEBI:3216
CAS Number
52485-79-7
TTD ID
D06AWE
INTEDE ID
DR0246
ACDINA ID
D00082

Full List of Drug Formulations Containing This Drug

Buprenorphine 2 mg tablet
Company Formulation ID FDA Description
Contract Pharmacal; RemedyRepack F02767 Anhydrous citric acid; Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Trisodium citrate dihydrate; Crospovidone; Povidone; Aluminum oxide; Starch, corn
Cardinal Health; RemedyRepack F02774 Anhydrous citric acid; Lactose monohydrate; Sodium citrate; Magnesium stearate; Mannitol; Crospovidone; Povidone; Starch, corn
Contract Pharmacal; Mylan Pharamceuticals; RemedyRepack F02765 Anhydrous citric acid; Anhydrous lactose; Lactose monohydrate; Sodium citrate, unspecified form; Magnesium stearate; Mannitol; Silicon dioxide; Crospovidone, unspecified; Microcrystalline cellulose; Starch, corn
RemedyRepack F02773 Anhydrous citric acid; Anhydrous lactose; Lactose monohydrate; Sodium citrate, unspecified form; Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Starch, corn
Lake Eire Medical & Surgical Supply DBA Quality Care Products F02769 Anhydrous citric acid; Lactose monohydrate; Sodium citrate; Magnesium stearate; Mannitol; Crospovidone; Povidones; Starch, corn
RemedyRepack F02775 Anhydrous citric acid; Lactose monohydrate; Sodium citrate; Magnesium stearate; Mannitol; Povidone; Starch, corn
RemedyRepack; Sun Pharmaceutical Industries F02776 Anhydrous citric acid; Lactose monohydrate; Sodium citrate; Magnesium stearate; Mannitol; Butylated hydroxyanisole; Povidones; Starch, corn
Actavis Pharma F02766 Anhydrous citric acid; Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Trisodium citrate dihydrate; Povidone k30; Crospovidone (15 mpa.s at 5%); Starch, corn
Contract Pharmacal; Teva Pharmaceuticals F02770 Anhydrous citric acid; Lactose monohydrate; Sodium citrate, unspecified form; Magnesium stearate; Mannitol; Povidone k30; Starch, corn
Contract Pharmacal; West-Ward Pharmaceticals F02768 Anhydrous citric acid; Lactose monohydrate; Sodium citrate, unspecified form; Magnesium stearate; Mannitol; Crospovidone (15 mpa.s at 5%); Povidones; Starch, corn
Rhodes Pharmaceuticals F02771 Anhydrous citric acid; Lactose monohydrate; Magnesium stearate; Mannitol; Trisodium citrate dihydrate; Povidone k30; Crospovidone, unspecified; Starch, corn
Bryant Ranch Prepack; Contract Pharmacal; Hi-Tech Pharmacal; RemedyRepack; TYA Pharmaceuticals F02772 Anhydrous citric acid; Lactose monohydrate; Sodium stearyl fumarate; Mannitol; Trisodium citrate dihydrate; Povidone k30
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⏷ Show the Full List of 12 Formulation(s)
Buprenorphine 8 mg tablet
Company Formulation ID FDA Description
Contract Pharmacal; RemedyRepack F02779 Anhydrous citric acid; Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Trisodium citrate dihydrate; Crospovidone; Povidone; Aluminum oxide; Starch, corn
Contract Pharmacal; Mylan Pharamceuticals F02777 Anhydrous citric acid; Anhydrous lactose; Lactose monohydrate; Sodium citrate, unspecified form; Magnesium stearate; Mannitol; Silicon dioxide; Crospovidone, unspecified; Microcrystalline cellulose; Starch, corn
Lake Eire Medical & Surgical Supply DBA Quality Care Products F02781 Anhydrous citric acid; Lactose monohydrate; Sodium citrate; Magnesium stearate; Mannitol; Crospovidone; Povidones; Starch, corn
Sun Pharmaceutical Industries F02786 Anhydrous citric acid; Lactose monohydrate; Sodium citrate; Magnesium stearate; Mannitol; Butylated hydroxyanisole; Povidones; Starch, corn
Actavis Pharma F02778 Anhydrous citric acid; Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Trisodium citrate dihydrate; Povidone k30; Crospovidone (15 mpa.s at 5%); Starch, corn
Contract Pharmacal; Teva Pharmaceuticals F02782 Anhydrous citric acid; Lactose monohydrate; Sodium citrate, unspecified form; Magnesium stearate; Mannitol; Povidone k30; Starch, corn
RemedyRepack F02785 Anhydrous citric acid; Lactose monohydrate; Anhydrous trisodium citrate; Sodium stearyl fumarate; Mannitol; Povidone k30; Starch, corn
Contract Pharmacal; PD-Rx Pharmaceuticals; West-Ward Pharmaceticals F02780 Anhydrous citric acid; Lactose monohydrate; Sodium citrate, unspecified form; Magnesium stearate; Mannitol; Crospovidone (15 mpa.s at 5%); Povidones; Starch, corn
Rhodes Pharmaceuticals F02783 Anhydrous citric acid; Lactose monohydrate; Magnesium stearate; Mannitol; Trisodium citrate dihydrate; Povidone k30; Crospovidone, unspecified; Starch, corn
A-S Medication Solutions; Aidarex Pharmaceuticals; Bryant Ranch Prepack; Contract Pharmacal; Hi-Tech Pharmacal; Lake Eire Medical & Surgical Supply DBA Quality Care Products; PD-Rx Pharmaceuticals; RemedyRepack; TYA Pharmaceuticals F02784 Anhydrous citric acid; Lactose monohydrate; Sodium stearyl fumarate; Mannitol; Trisodium citrate dihydrate; Povidone k30
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⏷ Show the Full List of 10 Formulation(s)
Buprenorphine Hydrochloride eq 0.5mg base film
Company Formulation ID FDA Description
Indivior F24424 Polyethylene Oxide; Hydroxypropyl Methylcellulose; Maltitol; AcesulfamePotassium; LimeFlavor; CitricAcid; SodiumCitrate; Fd&CYellow 6; WhiteInk
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Buprenorphine Hydrochloride eq 2mg base film
Company Formulation ID FDA Description
Indivior F24428 Polyethylene Oxide; Hydroxypropyl Methylcellulose; Maltitol; AcesulfamePotassium; LimeFlavor; CitricAcid; SodiumCitrate; Fd&CYellow 6; WhiteInk
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Buprenorphine Hydrochloride eq 2mg base tablet
Company Formulation ID FDA Description
Indivior F23391 Lactose; Mannitol; Cornstarch; PovidoneK30; CitricAcid; SodiumCitrateAndMagnesiumStearate
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Buprenorphine Hydrochloride eq 0.3mg base/ml injectable
Company Formulation ID FDA Description
Indivior F23390 Dextrose; Water; Hci
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References

1 Buprenorphine FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1670).
3 ClinicalTrials.gov (NCT02510014) Safety and Tolerability Study of Depot Buprenorphine in Treatment Seeking Subjects With Opioid Use Disorder.
4 ClinicalTrials.gov (NCT00941304) Study of BEMA Buprenorphine in the Treatment of Dental Pain. U.S. National Institutes of Health.