Details of the Drug Formulations

General Information of Drug (ID: DMR8ONJ)

Drug Name
Leflunomide Drug Info
Synonyms
Arava; Leflunomid; Leflunomida; Leflunomidum; Lefunamide; Aventis Behring Brand of Leflunomide; Aventis Brand of Leflunomide; Aventis Pharma Brand of Leflunomide; Hoechst Brand of Leflunomide; HWA 486; L 5025; SU 101; SU101; Arava (TN); Arava, Leflunomide; HWA-486; Leflunomida [INN-Spanish]; Leflunomide [USAN:INN]; Leflunomidum [INN-Latin]; Lefunomide [Inn-Spanish]; RS-34821; SU 101 (pharmaceutical); SU-101; AP-501/42475599; Leflunomide (JAN/USAN/INN); N-(4-trifluoromethyphenyl)-5-methylisoxazole-4-carboxamide; N-(4'-Trifluoromethylphenyl)-5-methylisoxazole-4-carboxamide; Alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-p-toluidide; 4-Isoxazolecarboxamide, 5-methyl-N-(4-(trifluoromethyl)phenyl; 4-isoxazolecarboxamide,5-methyl-N-(4-(trifluoromethyl)phenyl); 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide; 5-Methylisoxazole-4-(4-trifluoromethyl)carboxanilide; 5-Methylisoxazole-4-(4-trifluoromethylcarboxanilide); 5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide; 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide; 5-methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide; 5-methyl-N-[4-(trifluoromethyl)phenyl]isoxazole-4-carboxamide
Indication
Disease Entry ICD 11 Status REF
Arthritis FA20 Approved [1]
Lupus nephritis 4A40.0Y Approved [2]
Multiple sclerosis 8A40 Approved [3]
Psoriatic arthritis FA21 Approved [2]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 1 [4]
Therapeutic Class
Antiinflammatory Agents
Cross-matching ID
PubChem CID
3899
ChEBI ID
CHEBI:6402
CAS Number
75706-12-6
TTD ID
D08ROP
VARIDT ID
DR00130
INTEDE ID
DR0921
ACDINA ID
D00352

Full List of Drug Formulations Containing This Drug

Leflunomide 10 mg tablet
Company Formulation ID FDA Description
Physicians Total Care F11343 Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Hypromellose; Polysorbate 80; Povidone; Colloidal silicon dioxide; Polyethylene glycol; Starch, corn
Teva Pharmaceuticals F11347 Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Triacetin; Crospovidone; Polyethylene glycol 3350; Silicon dioxide; Hypromelloses; Povidone k29/32; Starch, corn
NorthStar Rx F11348 Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycol 8000; Starch, corn
Alembic Pharmaceuticals; Trigen Laboratories F11349 Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols; Starch, corn
Prasco F11350 Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols
Sandoz F11346 Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycol; Starch, corn
Heritage Pharmaceuticals F11344 Lactose monohydrate; Magnesium stearate; Talc; Croscarmellose sodium; Silicon dioxide; Starch, corn
Apotex F11342 Anhydrous lactose; Magnesium stearate; Crospovidone; Silicon dioxide
Golden State Medical Supply F11345 Anhydrous lactose; Magnesium stearate; Crospovidone; Silicon dioxide
Winthrop F11351 Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols; Povidones
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⏷ Show the Full List of 10 Formulation(s)
Leflunomide 20 mg tablet
Company Formulation ID FDA Description
Physicians Total Care F11353 Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Hypromellose; Polysorbate 80; Povidone; Colloidal silicon dioxide; Polyethylene glycol; Starch, corn
Teva Pharmaceuticals F11356 Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Crospovidone; Polyethylene glycol 3350; Silicon dioxide; Hypromelloses; Povidone k29/32; Starch, corn
NorthStar Rx F11357 Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Crospovidone; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycol 8000; Starch, corn
Alembic Pharmaceuticals; Avera McKennan Hospital; Trigen Laboratories F11358 Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Crospovidone; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols; Starch, corn
Prasco F11360 Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Crospovidone; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols
Bryant Ranch Prepack F11359 Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Hypromelloses; Polyethylene glycols; Povidones
Dispensing Solution; Heritage Pharmaceuticals F11354 Lactose monohydrate; Magnesium stearate; Talc; Croscarmellose sodium; Silicon dioxide; Starch, corn
Apotex F11352 Anhydrous lactose; Magnesium stearate; Crospovidone; Silicon dioxide
Golden State Medical Supply F11355 Anhydrous lactose; Magnesium stearate; Crospovidone; Silicon dioxide
Winthrop F11361 Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols; Povidones
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⏷ Show the Full List of 10 Formulation(s)

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6825).
2 Leflunomide FDA Label
3 FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (ANDA) 077090.
4 ClinicalTrials.gov (NCT04361214) Leflunomide in Mild COVID-19 Patients. U.S. National Institutes of Health.