Details of the Drug Formulations

General Information of Drug (ID: DMRICNP)

Drug Name
Vandetanib Drug Info
Synonyms
Zactima; Vandetanib [INN]; CH 331; ZD 6474; ZD6474; AZD-6474; CH-331; F9995-0087; ZD-6474; Zactima, ZD6474; Vandetanib (JAN/INN); Vandetanib, Zactima, ZD6474; N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine; N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-4-quinazolinamine; N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine; 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline; Vandetanib (Pan-TK inhibitor)
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Approved [1]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
3081361
ChEBI ID
CHEBI:49960
CAS Number
443913-73-3
TTD ID
D0G6QF
VARIDT ID
DR00618
INTEDE ID
DR1669
ACDINA ID
D00720

Full List of Drug Formulations Containing This Drug

Vandetanib 100 mg tablet
Company Formulation ID FDA Description
AstraZeneca F22130 Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Water; Crospovidone; Polyethylene glycol 300; Povidone; Cellulose, microcrystalline; Hypromelloses
AstraZeneca F22129 Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Water; Polyethylene glycol 300; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Povidones
Genzyme Corporation F22131 Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Water; Polyethylene glycol 300; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Povidone, unspecified
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Vandetanib 300 mg tablet
Company Formulation ID FDA Description
AstraZeneca F22133 Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Water; Crospovidone; Polyethylene glycol 300; Povidone; Cellulose, microcrystalline; Hypromelloses
AstraZeneca F22132 Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Water; Polyethylene glycol 300; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Povidones
Genzyme Corporation F22134 Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Water; Polyethylene glycol 300; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Povidone, unspecified
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5717).