Details of the Drug Formulations

General Information of Drug (ID: DMUDIR8)

• Drug Name: Fludrocortisone Drug Info
• Synonyms: fludrocortisone; Fluorocortisone; Fluorocortisol; Fluohydrisone; Florinef; Fluohydrocortisone; Astonin-H; Fludrocortone; Alflorone; Fludronef; Fludrone; Fluodrocortisone; 127-31-1; F-Cortef; 9alpha-Fluorocortisol; Fludrocortisona; Fludrocortisonum; F-COL; 9-Fluorocortisol; 9 alpha FF; 9-Fluorohydrocortisone; Cortisol, 9-fluoro-; StC 1400; 9alpha-Fludrocortisone; 9-AFH; 9-alpha-Fluorocortisol; 9-alpha-Fludrocortisone; Fludrocortisonum [INN-Latin]; Fludrocortisona [INN-Spanish]; 9-AF; Alflorone; Astonin; FCOL; Astonin H; Astonin Merck; Merck Brand of Fludrocortisone; U 5963; ZK5; F-Cortef;Florinef (TN); Fludrocortisone (INN); Fludrocortisone [INN:BAN]; Merck, Astonin; Astonin-H (TN); Hydrocortisone-9alpha-fluoro; Pregn-4-ene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-(8CI); (11beta)-9-Fluoro-11,17,21-trihydroxypregn-4-ene-3,20-dione; (8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one; 9 Fluoro 17 Hydroxycortisone; 9 Fluorocortisol; 9 Fluorohydrocortisone; 9 alpha Fludrohydrocortisone; 9 alpha Fluoro 17 Hydroxycorticosterone; 9 alpha Fluorohydrocortisone; 9 alpha-Fludrocortisone; 9 alpha-Fluoro-17-Hydroxycorticosterone; 9 alpha-Fluorocortisol; 9 alpha-Fluorohydrocortisone; 9-Fluoro-11-beta,17,21-trihydroxypregn-4-ene-3,20-dione; 9-Fluoro-11beta,17,21-trihydroxypregn-4-ene-3,20-dione; 9-Fluoro-17-Hydroxycortisone; 9-alpha-Fluoro-17-hydroxycorticosterone; 9-alpha-Fluorohydrocortisone; 9alpha-Fluoro-11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione; 9alpha-Fluoro-17-hydroxycorticosterone; 9alpha-Fluorohydrocortisone; 9alpha-Fluoro-hydrocortisone

Indication

Disease Entry	ICD 11	Status	REF
Addison disease	5A74.0	Approved	[1]
Cerebral salt-wasting syndrome	5C72	Approved	[2]
Congenital adrenal hyperplasia	5A71.01	Approved	[1]

• Therapeutic Class: Antiinflammatory Agents
• Cross-matching ID:
  PubChem CID: 31378
  ChEBI ID: CHEBI:50885
  CAS Number: 127-31-1
  TTD ID: D0R7JT
  INTEDE ID: DR0705
  ACDINA ID: D00282

Full List of Drug Formulations Containing This Drug

Fludrocortisone 0.1 mg tablet

Company	Formulation ID	FDA Description
RemedyRepack	F08410	Anhydrous lactose; D&c yellow no. 10; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Aluminum oxide; Sodium starch glycolate type a potato; Starch, corn
PD-Rx Pharmaceuticals	F08411	Anhydrous lactose; D&c yellow no. 10; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Talc; Aluminum oxide; Sodium starch glycolate type a potato; Starch, corn
Teva Pharmaceuticals	F08412	Anhydrous lactose; D&c yellow no. 10; Magnesium stearate; Dibasic calcium phosphate dihydrate; Talc; Sodium starch glycolate type a potato; Starch, corn
American Health Packaging; AvKARE; AvPAK; Cardinal Health; Impax Generics; NCS HealthCare of KY, Inc dba Vangard Labs; Physicians Total Care	F08413	Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Cellulose, microcrystalline
West-Ward Pharmaceticals	F08409	Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Talc; Corn starch 3-e-dodecenyl succinic anhydride modified

Fludrocortisone Acetate 0.1mg tablet

Company	Formulation ID	FDA Description
Teva Pharmaceuticals Usa	F23452	Anhydrous Lactose; Starch, Corn; Dibasic Calcium Phosphate Dihydrate; D&C Yellow No. 10 Aluminum Lake; Magnesium Stearate; Sodium Starch Glycolate Type A Potato; Talc
Amneal Pharmaceuticals Ny	F23453	Croscarmellose Sodium; Lactose Monohydrate; Magnesium Stearate; Cellulose, Microcrystalline
Cardinal Health	F23454	Croscarmellose Sodium; Lactose Monohydrate; Magnesium Stearate; Microcrystalline Cellulose

References

• [1] Fludrocortisone FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2873).