Details of the Drug Formulations

General Information of Drug (ID: DMUOT9V)

• Drug Name: Taxol Drug Info
• Synonyms: C47H51NO14; weekly paclitaxel; Micellar Paclitaxel; Paclitaxel [USAN:INN:BAN]; SCHEMBL15000506; Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha,12aalpha,12balpha))-

Indication

Disease Entry	ICD 11	Status	REF
Breast cancer	2C60-2C65	Approved	[1]
Solid tumour/cancer	2A00-2F9Z	Approved	[2]
Pancreatic cancer	2C10	Phase 3	[3]
Gastric adenocarcinoma	2B72	Phase 2	[4]
Ovarian cancer	2C73	Phase 2	[4]

• Cross-matching ID:
  PubChem CID: 36314
  ChEBI ID: CHEBI:45863
  CAS Number: 33069-62-4
  TTD ID: D0C4RB
  ACDINA ID: D01313

Full List of Drug Formulations Containing This Drug

Paclitaxel 6mg/ml injectable

Company	Formulation ID	FDA Description
Msn Laboratories Private Limited	F23859	Citric Acid; Dehydrated Alcohol; Purified Polyoxyl 35 Castor Oil
Actavis Pharma	F23860	Purified Cremophor El (Polyoxyethylated Castor Oil); Citric Acid Anhydrous; Dehydrated Alcohol
Wg Critical Care	F23861	Purified Polyoxl 35 Castor Oil; Dehydrated Alcohol

References

• [1] Paclitaxel directly binds to Bcl-2 and functionally mimics activity of Nur77. Cancer Res. 2009 Sep 1;69(17):6906-14.
• [2] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
• [3] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [4] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)