Details of the Drug Formulations

General Information of Drug (ID: DMVP5YE)

Drug Name
Doxorubicin Drug Info
Synonyms
doxorubicin; 23214-92-8; Doxil; Doxorubicine; Adriablastin; Doxorubicinum; 14-Hydroxydaunomycin; 14-Hydroxydaunorubicine; Doxorubicina; Adriamycin semiquinone; Doxorubicinum [INN-Latin]; Doxorubicine [INN-French]; Doxorubicina [INN-Spanish]; Myocet; FI 106; Doxorubicin [USAN:INN:BAN]; CCRIS 739; NDC 38242-874; HSDB 3070; UNII-80168379AG; NCI-C01514; EINECS 245-495-6; CHEMBL53463; CHEBI:28748; 5,12-Naphthacenedione,; ADM; ADR; ThermoDox; Aerosolized Doxorubicin; Doxorubicin citrate; RDF Rubex; Conjugate of doxorubicin with humanized monoclonal antibody LL1 against CD74; DM2; JT9100000; Adiblastine (hydrochloride salt); Adr iablatina (hydrochloride salt); Adriablastine (hydrochloride salt); Adriablatina (hydrochloride salt); Adriacin (hydrochloride salt); Adriamycin PFS (TN); Adriamycin PFS (hydrochloride salt); Adriamycin RDF (TN); Adriamycin RDF (hydrochloride salt); Adriblastina (TN); Adriblastina (hydrochloride salt); Adriblatina (hydrochloride salt); Caelyx (TN); Conjugate of doxorubicin with monoclonal antibody P4/D10 against GP120; DOX-SL; Doxorubicin hydrochloride (hydrochloride salt); Doxorubicin-hLL1; Doxorubicin-hLL1 conjugate; Farmablastina (hydrochloride salt); Hydroxydaunomycin hydrochlor ide (hydrochloride salt); Hydroxydaunomycin hydrochloride (hydrochloride salt); Hydroxydaunorubicin hydrochloride (hydrochloride salt); Myocet (TN); Rubex (TN); Rubex (hydrochloride salt); TLC D-99; Doxorubicin (USAN/INN); Doxorubicin-P4/D10; Doxorubicin-P4/D10 conjugate; Cantide + adriamycin
Indication
Disease Entry ICD 11 Status REF
Acute myelogenous leukaemia 2A41 Approved [1]
Adult kidney Wilms tumor Approved [1]
Anterior urethra cancer Approved [1]
Beckwith-Wiedemann syndrome Approved [1]
Breast carcinoma Approved [1]
Burkitt lymphoma Approved [1]
Carcinoma 2A00-2F9Z Approved [1]
Childhood kidney Wilms tumor Approved [1]
Epithelial ovarian cancer 2B5D Approved [1]
Fallopian tube neoplasm Approved [1]
Hamartoma Approved [1]
Hormone-resistant prostate carcinoma Approved [1]
Inflammatory breast cancer 2C62 Approved [1]
Kaposi sarcoma 2B57 Approved [1]
Kidney neoplasm Approved [1]
Leukemia Approved [1]
Lung cancer 2C25.0 Approved [1]
MALT lymphoma Approved [1]
Nodal marginal zone lymphoma 2A85.0 Approved [1]
Ovarian disorder Approved [1]
Ovarian neoplasm Approved [1]
Plasma cell myeloma 2A83.1 Approved [1]
Posterior urethra cancer Approved [1]
Primary systemic amyloidosis Approved [1]
Small-cell lung cancer 2C25.Y Approved [1]
Solid tumour/cancer 2A00-2F9Z Approved [2]
Splenic marginal zone lymphoma Approved [1]
Testicular lymphoma Approved [1]
Thyroid cancer 2D10 Approved [1]
Wilms tumor Approved [1]
Hepatocellular carcinoma 2C12.02 Phase 3 [3]
Breast cancer 2C60-2C65 Phase 2 [4]
Classic Hodgkin lymphoma Investigative [1]
Follicular lymphoma 2A80 Investigative [1]
Neuroblastoma 2D11.2 Investigative [1]
Tumour 2A00-2F9Z Investigative [5]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
31703
ChEBI ID
CHEBI:28748
CAS Number
23214-92-8
TTD ID
D07VLY
VARIDT ID
DR00301
INTEDE ID
DR0546

Full List of Drug Formulations Containing This Drug

Doxorubicin Hydrochloride 20mg/10ml liposomaldispersion
Company Formulation ID FDA Description
Baxter Healthcare Corporation F23722 Sodium N-Carbonyl-Methoxypolyethylene Glycol 2000-1, 2-Distearoyl-Sn-Glycero-3-Phosphoethanolamine; Cholesterol; Hydrogenated Soybean Lecithin; Ammonium Sulfate; Histidine; Hydrochloric Acid; Sodium Hydroxide; Sucrose
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Doxorubicin Hydrochloride 10mg/5ml solution
Company Formulation ID FDA Description
Actavis Pharma F24335 Sodium Chloride; Water; Hydrochloric Acid
Pfizer Laboratories Div Pfizer F24334 Sodium Chloride; Hydrochloric Acid
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Doxorubicin Hydrochloride 20mg/10ml solution
Company Formulation ID FDA Description
Actavis Pharma F24369 Sodium Chloride; Water; Hydrochloric Acid
Pfizer Laboratories Div Pfizer F24368 Sodium Chloride; Hydrochloric Acid
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Doxorubicin Hydrochloride 50mg/25ml solution
Company Formulation ID FDA Description
Actavis Pharma F24403 Sodium Chloride; Water; Hydrochloric Acid
Pfizer Laboratories Div Pfizer F24402 Sodium Chloride; Hydrochloric Acid
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References

1 Doxorubicin FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7069).
3 ClinicalTrials.gov (NCT02112656) Study of ThermoDox With Standardized Radiofrequency Ablation (RFA) for Treatment of Hepatocellular Carcinoma (HCC) (OPTIMA). U.S. National Institutes of Health.
4 Antitumor activity of liposome-encapsulated doxorubicin in advanced breast cancer: phase II study. J Natl Cancer Inst. 1990 Nov 7;82(21):1706-10.
5 Design and development of antisense drugs. Expert Opin. Drug Discov. 2008 3(10):1189-1207.