Details of the Drug Formulations

General Information of Drug (ID: DMWA2DZ)

• Drug Name: Berotralstat Drug Info
• Synonyms: UNII-XZA0KB1BDQ; XZA0KB1BDQ; 1809010-50-1; BCX7353; BCX-7353; Berotralstat (USAN); Berotralstat [USAN]; 1-[3-(aminomethyl)phenyl]-N-(5-{(R)-(3-; cyanophenyl)[(cyclopropylmethyl)amino]methyl}-2-; fluorophenyl)-3-(trifluoromethyl)-1H-pyrazole-5-; Orladeyo; Berotralstat [INN]; Berotralstat [USAN:INN]; SCHEMBL21974728; GTPL11347; WHO 10907; D11673; 1-(3-(Aminomethyl)phenyl)-N-(5-((R)-(3-cyanophenyl)((cyclopropylmethyl)amino)methyl)-2-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide; 1H-pyrazole-5-carboxamide, 1-(3-(aminomethyl)phenyl)-N-(5-((R)-(3-cyanophenyl)((cyclopropylmethyl); 1H-Pyrazole-5-carboxamide, 1-(3-(aminomethyl)phenyl)-N-(5-((R)-(3-cyanophenyl)((cyclopropylmethyl)amino)methyl)-2-fluorophenyl)-3-(trifluoromethyl)-; 2-[3-(aminomethyl)phenyl]-N-[5-[(R)-(3-cyanophenyl)-(cyclopropylmethylamino)methyl]-2-fluorophenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide

Indication

Disease Entry	ICD 11	Status	REF
Hereditary angioedema	4A00.14	Approved	[1]

• Cross-matching ID:
  PubChem CID: 137528262
  CAS Number: 1809010-50-1
  TTD ID: DQ1S0B
  ACDINA ID: D00877

Full List of Drug Formulations Containing This Drug

Berotralstat eq 110mg base capsule

Company	Formulation ID	FDA Description
Biocryst	F24026	Colloidal Silicon Dioxide; Crospovidone; Magnesium Stearate; Pregelatinized Starch

Berotralstat eq 150mg base capsule

Company	Formulation ID	FDA Description
Biocryst	F24027	Colloidal Silicon Dioxide; Crospovidone; Magnesium Stearate; Pregelatinized Starch

References

• [1] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2020