Details of the Drug Formulations

General Information of Drug (ID: DMX6RTG)

• Drug Name: Trospium Drug Info
• Synonyms: Spasmex; Spasmoplex; Trosec; Regurin (TN); Sanctura (TN); Spasmex (TN); Spasmoplex (TN); Trosec (TN); Trospium chloride (JAN/USAN/INN); Spiro(8-azoniabicyclo(3.2.1)octane-8,1'-pyrrolidinium), 3-hydroxy-, chloride, benzilate; Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-yl 2-hydroxy-2,2-diphenylacetate; Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-yl 2-hydroxy-2,2-diphenylacetate chloride; 3-Hydroxyspiro(8-azoniabicyclo(3.2.1)octane-8,1'-pyrrolidinium) chloride benzilate; 6,10-Ethano-5-azoniaspiro(4.5)decan-8-ol, chloride, benzilate; 8-Benziloyloxy-6,10-ethano-5-azoniaspiro(4.5)decane chloride

Indication

Disease Entry	ICD 11	Status	REF
Overactive bladder	GC50.0	Approved	[1]
Spasm	MB47.3	Approved	[1]
Neurogenic detrusor overactivity	GC01	Phase 1	[2]
Priapism		Investigative	[3]

• Therapeutic Class: Parasympatholytics
• Cross-matching ID:
  PubChem CID: 5284632
  ChEBI ID: CHEBI:145791
  CAS Number: 47608-32-2
  TTD ID: D05TIB
  ACDINA ID: D00710

Full List of Drug Formulations Containing This Drug

Trospium 60 mg capsule

Company	Formulation ID	FDA Description
Actavis Pharma; BluePoint Laboratories	F21735	D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Polyethylene glycol 4000; Polysorbate 80; Polyvinyl alcohol; Ethylcellulose (10 mpa.s); Gelatin; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Poly(methyl acrylate-co-methyl methacrylate-co-methacrylic acid 7:3:1 280000 mw); Shellac; Starch, corn
Golden State Medical Supply	F21736	D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Polyethylene glycol 4000; Polysorbate 80; Ethylcellulose (10 mpa.s); Gelatin, unspecified; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Poly(methyl acrylate-co-methyl methacrylate-co-methacrylic acid 7:3:1 280000 mw); Polyvinyl alcohol, unspecified; Shellac; Starch, corn
Paddock Laboratories,	F21737	Stearic acid; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Magnesium aluminum silicate; Potassium hydroxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Gelatin; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Shellac
Physicians Total Care	F21725	Talc; Triethyl citrate
Allergan	F21738	Talc; Triethyl citrate

Trospium 20 mg tablet

Company	Formulation ID	FDA Description
Allergan	F21734	Stearic acid; Lactose monohydrate; Calcium carbonate; Magnesium stearate; Ferric oxide red; Sucrose; Talc; Titanium dioxide; Carboxymethylcellulose sodium; Croscarmellose sodium; Povidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Polyethylene glycol 8000; Starch, wheat; White wax
Cipla; Exelan Pharmaceuticals	F21733	Lactose monohydrate; Sucralose; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Xylitol; Croscarmellose sodium; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Hypromelloses; Microcrystalline cellulose
Paddock Laboratories,	F21727	Stearic acid; Lactose monohydrate; Calcium carbonate; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 3350; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Povidones
Heritage Pharmaceuticals	F21726	Lactose monohydrate; Butyl alcohol; Magnesium stearate; Ferric oxide red; Propylene glycol; Sucrose; Talc; Titanium dioxide; Croscarmellose sodium; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Shellac
Biomes Pharmaceuticals	F21728	Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Povidone; Silicon dioxide; Cellulose, microcrystalline; Copovidone k25-31; Croscarmellose; Hypromelloses; Starch, corn
Glenmark Pharmaceutials	F21729	Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Sucrose; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Polyethylene glycol 6000; Silicon dioxide; Cellulose, microcrystalline; Copovidone k25-31; Hypromelloses; Povidones; Starch, corn
AvKARE	F21730	Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (1200000 mw); Hypromellose 2906 (4000 mpa.s); Polyethylene glycol 8000
Golden State Medical Supply	F21731	Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2906 (4000 mpa.s); Polyethylene glycol 8000
Apotex	F21732	Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromellose 2906 (4000 mpa.s); Polyethylene glycol 8000

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7480).
• [2] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [3] Trospium FDA Label