Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM08XIN)

Drug Name
EPIANDROSTERONE Drug Info
Synonyms
EPIANDROSTERONE; 481-29-8; trans-Androsterone; Isoandrosterone; 3Beta-hydroxy-5alpha-androstan-17-one; 3beta-Hydroxyetioallocholan-17-one; epi-andosterone; 5alpha-Androstan-3beta-ol-17-one; iso-Androsterone; d-Epiandrosterone; UNII-8TR252Z538; 3-Epiandrosterone; (3beta,5alpha)-3-hydroxyandrostan-17-one; CHEMBL272195; 3beta-Hydroxy-androstan-17-one; CHEBI:541975; QGXBDMJGAMFCBF-LUJOEAJASA-N; Androsterone, epi-; NSC 93996; MFCD00064134; 8TR252Z538; ST072176; Androstan-17-one, 3-hydroxy-, (3b,5a)-; epi-Androsterone; C19H30O2
Cross-matching ID
PubChem CID
441302
ChEBI ID
CHEBI:541975
CAS Number
CAS 481-29-8
TTD Drug ID
DM08XIN

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glucose-6-phosphate dehydrogenase (G6PD) TTKN8W0 G6PD_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Glucose-6-phosphate dehydrogenase (G6PD) DTT G6PD 3.868 3.733 5.853 5.498
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Glucose-6-phosphate dehydrogenase (G6PD) DTT G6PD 4.01E-01 -0.18 -0.3
Glucose-6-phosphate dehydrogenase (G6PD) DTT G6PD 2.39E-03 0.44 0.6
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Inhibition of Trypanosoma brucei glucose-6-phosphate dehydrogenase by human steroids and their effects on the viability of cultured parasites. Bioorg Med Chem. 2009 Mar 15;17(6):2483-9.