Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM0GOUD)

Drug Name
Urokinase Drug Info
Indication
Disease Entry ICD 11 Status REF
Myocardial infarction BA41-BA43 Approved [1]
Pulmonary embolism BB00 Approved [2]
Therapeutic Class
Thrombolytic Agents
Cross-matching ID
PubChem CID
33309
TTD Drug ID
DM0GOUD

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Urokinase-type plasminogen activator (PLAU) TTGY7WI UROK_HUMAN Modulator [3]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Urokinase-type plasminogen activator (PLAU) DTT PLAU 5.352 5.741 6.924 6.898
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Myocardial infarction
ICD Disease Classification BA41-BA43
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Urokinase-type plasminogen activator (PLAU) DTT PLAU 5.32E-70 1.07 1.82
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Emerging drugs in peripheral arterial disease. Expert Opin Emerg Drugs. 2006 Mar;11(1):75-90.
2 Comparative Efficacy and Safety of Thrombolytic Agents for Pulmonary Embolism: A Bayesian Network Meta-Analysis. Pharmacology. 2023;108(2):111-126.
3 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.