Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM0OYLQ)

Drug Name

I-vation Drug Info

Synonyms

Triamcinolone implant

Indication

Disease Entry	ICD 11	Status	REF
Diabetic retinopathy	9B71.0	Phase 2	[1]

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Corticosteroid-binding globulin (SERPINA6)	TTJL8VG	CBG_HUMAN	Modulator	[2]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Corticosteroid-binding globulin (SERPINA6)	DTT	SERPINA6	9.968	3.722	6.732	5.76

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Diabetic retinopathy

ICD Disease Classification

9B71.0

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Corticosteroid-binding globulin (SERPINA6)	DTT	SERPINA6	3.29E-04	-0.2	-0.2

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Drug delivery implants in the treatment of vitreous inflammation. Mediators Inflamm. 2013;2013:780634.
2	Cortisol binding in rat skeletal muscle. J Biol Chem. 1975 Feb 25;250(4):1207-11.