Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM12EYR)

Drug Name
R348 Drug Info
Indication
Disease Entry ICD 11 Status REF
Psoriasis vulgaris EA90 Terminated [1]
Cross-matching ID
PubChem CID
68254
CAS Number
CAS 529-21-5
TTD Drug ID
DM12EYR

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Janus kinase 3 (JAK-3) TTT7PJU JAK3_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Janus kinase 3 (JAK-3) DTT JAK3 2.104 3.248 2.848 4.485
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Psoriasis vulgaris
ICD Disease Classification EA90
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Janus kinase 3 (JAK-3) DTT JAK3 4.94E-03 0.28 1.41
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Emerging drugs for psoriasis. Expert Opin Emerg Drugs. 2009 Mar;14(1):145-63.