General Information of Drug (ID: DM19I62)

Drug Name
7-Phloroethol Drug Info
Synonyms
7-Phloroeckol; 7-Phloroethol; UNII-97GCC12YF0; CHEMBL456228; 97GCC12YF0; CHEBI:65790; 4-(3,5-dihydroxyphenoxy)-8-(2,4,6-trihydroxyphenoxy)oxanthrene-1,3,6-triol; 1-(3',5'-Dihydroxyphenoxy)-7-(2'',4'',6''-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4-dioxin; 7-Phloroglucinoleckol; SCHEMBL10271928; BDBM50276826; 4-(3,5-Dihydroxyphenoxy)-8-(2,4,6-trihydroxyphenoxy)dibenzo(b,E)(1,4)dioxin-1,3,6-triol; [(2,4,9-Trihydroxydibenzo-p-dioxin-1,7-diyl)dioxydibenzene]-2',3,4',5,6'-pentol; Dibenzo(b,E)(1,4)dioxin-1,3,6-triol, 4-(3,
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
10480940
ChEBI ID
CHEBI:65790
CAS Number
CAS 662165-35-7
TTD Drug ID
DM19I62

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Beta-secretase (BACE) TT8JRS7 NOUNIPROTAC Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Beta-secretase (BACE) DTT BACE 5.928 4.638 6.443 5.3
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Beta-secretase (BACE) DTT NO-GeName 6.98E-04 1.03 2.84
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Molecular docking studies of phlorotannins from Eisenia bicyclis with BACE1 inhibitory activity. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3211-5.