Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM1BKA6)

Drug Name
Opicapone Drug Info
Synonyms BIA-9-1067
Indication
Disease Entry ICD 11 Status REF
Parkinson disease 8A00.0 Approved [1]
Cross-matching ID
PubChem CID
135565903
ChEBI ID
CHEBI:134699
CAS Number
CAS 923287-50-7
TTD Drug ID
DM1BKA6
ACDINA Drug ID
D01302

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Catechol-O-methyl-transferase (COMT) TTKWFB8 COMT_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Catechol-O-methyl-transferase (COMT) DTT COMT 8.791 7.048 7.478 7.165
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Parkinson disease
ICD Disease Classification 8A00.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Catechol-O-methyl-transferase (COMT) DTT COMT 9.24E-02 0.17 1.09
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2020