Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM1DYU4)

Drug Name

9-octadecynoic acid Drug Info

Synonyms

Stearolic acid; 9-Octadecynoic acid; Octadec-9-ynoic acid; 506-24-1; 9-Stearolic acid; Delta(9)-octadecynoic acid; CHEMBL482804; CHEBI:28801; RGTIBVZDHOMOKC-UHFFFAOYSA-N; Stearolsaeure; Octadec-9-insaeure; EINECS 208-030-8; Octadeca-9-ynoic acid; 9-ODYA; 9-ODA; SCHEMBL196385; AC1L296J; MEGxp0_001740; AC1Q5W60; CTK1H2272; ACon1_002039; DTXSID90198647; MolPort-001-742-497; ZINC8221125; SBB069546; BDBM50292401; MFCD00014386; LMFA01030455; AKOS025117038; NCGC00179891-01; AN-45417; 9a-18:1; FT-0621682; C08459; 506S241; C-51779

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 68167
ChEBI ID: CHEBI:28801
CAS Number: CAS 506-24-1
TTD Drug ID: DM1DYU4

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
HMG-CoA reductase (HMGCR)	TTPADOQ	HMDH_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
HMG-CoA reductase (HMGCR)	DTT	HMGCR	6.357	6.256	5.17	6.85

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
HMG-CoA reductase (HMGCR)	DTT	HMGCR	1.01E-05	0.65	1.53

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Novel Acetylenic Acids from the Root Bark of Paramacrolobium caeruleum: Inhibitors of 3-Hydroxy-3-methyl-glutaryl Coenzyme A Reductase J. Nat. Prod. 52(1):153-161 (1989).