Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM1FX09)

Drug Name
DT-TX-30 Drug Info
Synonyms DT-TX-30-SE
Indication
Disease Entry ICD 11 Status REF
Angina pectoris BA40 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DM1FX09

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Thromboxane A2 receptor (TBXA2R) TT2O84V TA2R_HUMAN Antagonist [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Thromboxane A2 receptor (TBXA2R) DTT TBXA2R 6.075 5.925 6.729 6.096
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Angina pectoris
ICD Disease Classification BA40
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Thromboxane A2 receptor (TBXA2R) DTT TBXA2R 2.78E-04 -0.11 -0.31
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 DTTX30, a combined thromboxane receptor antagonist and thromboxane synthetase inhibitor, prevents coronary thrombosis in anesthetized dogs. Basic Res Cardiol. 1997 Jun;92(3):181-90.