Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM1KBAY)

Drug Name
A-93178 Drug Info
Synonyms A-93178.5
Indication
Disease Entry ICD 11 Status REF
Allergy 4A80-4A85 Terminated [1]
Cross-matching ID
PubChem CID
101018054
TTD Drug ID
DM1KBAY

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Arachidonate 5-lipoxygenase activating protein (FLAP) TTDMBF5 AL5AP_HUMAN Modulator [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Arachidonate 5-lipoxygenase activating protein (FLAP) DTT ALOX5AP 7.104 8.149 7.984 7.741
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Allergy
ICD Disease Classification 4A80-4A85
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Arachidonate 5-lipoxygenase activating protein (FLAP) DTT ALOX5AP 9.89E-01 -0.06 -0.05
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Characterization of A-93178, an iminoxy-quinoline inhibitor of leukotriene biosynthesis. Adv Exp Med Biol. 1997;433:91-4.