Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM28D9E)

Drug Name

(1R,2S)-1,2-diphenylethane-1,2-diamine Drug Info

Synonyms

meso-1,2-Diphenylethylenediamine; 951-87-1; CHEMBL206743; (1S,2R)-1,2-diphenylethane-1,2-diamine; Racemic stilbenediamine; AC1OC2I9; SCHEMBL2067094; MolPort-002-746-466; ZINC6581845; STK689613; BDBM50178427; BBL104274; AKOS005602166; MCULE-2915779897; meso-1,2-Diphenylethylenediamine, 98%; SC-21360; ST084935; AJ-94609; AS-11936; AB1010174; Z3396

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 6931234
TTD Drug ID: DM28D9E

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Dipeptidyl peptidase 4 (DPP-4)	TTDIGC1	DPP4_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Dipeptidyl peptidase 4 (DPP-4)	DTT	DPP4	4.995	4.926	7.852	8.358

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Dipeptidyl peptidase 4 (DPP-4)	DTT	DPP4	9.54E-01	-0.27	-1.85

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	In silico fragment-based discovery of DPP-IV S1 pocket binders. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1405-9.