General Information of Drug (ID: DM2FLRQ)

Drug Name
DIDODECANOYLPHLOROGLUCINOL Drug Info
Synonyms
DIDODECANOYLPHLOROGLUCINOL; CHEMBL470757; SCHEMBL9188500; MolPort-044-550-959; BDBM50256011; ZINC44417494; 1,1''-(2,4,6-trihydroxy-1,3-phenylene)didodecan-1-one; 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis-1-dodecanone; 1,1'-(2,4,6-Trihydroxy-1,3-phenylene)bis(dodecan-1-one)
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
9957245
TTD Drug ID
DM2FLRQ

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Group IIA phospholipase A2 (GIIA sPLA2) TTO8QRU PA2GA_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Group IIA phospholipase A2 (GIIA sPLA2) DTT PLA2G2A 9.464 8.495 5.655 10.995
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Group IIA phospholipase A2 (GIIA sPLA2) DTT PLA2G2A 6.13E-08 -0.54 -0.33
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Simplified YM-26734 inhibitors of secreted phospholipase A2 group IIA. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5415-9.