Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM2L9CO)

Drug Name
Ezatiostat Drug Info
Synonyms Telintra (TN)
Indication
Disease Entry ICD 11 Status REF
Myelodysplastic syndrome 2A37 Phase 2 [1]
Cross-matching ID
PubChem CID
5310939
CAS Number
CAS 168682-53-9
TTD Drug ID
DM2L9CO

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glutathione S-transferase P (GSTP1) TT40K12 GSTP1_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Glutathione S-transferase P (GSTP1) DTT GSTP1 7.068 8.612 9.074 8.459
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

ICD Disease Classification 02 Neoplasm
Disease Class ICD-11: 2C82 Prostate cancer
The Studied Tissue Bone marrow
The Studied Disease Myelodysplastic syndrome [ICD-11:2C82]
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Glutathione S-transferase P (GSTP1) DTT GSTP1 4.46E-01 1.42E-02 0.03
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT01422486) Phase 2 Study of Telintra in Deletion 5q Myelodysplastic Syndrome. U.S. National Institutes of Health.
2 National Cancer Institute Drug Dictionary (drug id 485244).