Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM3AW8X)

Drug Name

Nerve growth factor conjugated RAP peptide Drug Info

Synonyms

NGF-RAP; Nerve growth factor conjugated RAP peptide (NeuroTrans, neurodegenrative disease); Nerve growth factor conjugated RAP peptide (NeuroTrans, neurodegenrative disease), Raptor

Indication

Disease Entry	ICD 11	Status	REF
Neurodegenerative disorder	8A20-8A23	Investigative	[1]

Cross-matching ID

TTD Drug ID: DM3AW8X

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Low-affinity nerve growth factor receptor (NGFR)	TTEDJN4	TNR16_HUMAN	Modulator	[1]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Low-affinity nerve growth factor receptor (NGFR)	DTT	NGFR	5.524	1.848	2.807	2.678

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Neurodegenerative disorder

ICD Disease Classification

8A20-8A23

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Low-affinity nerve growth factor receptor (NGFR)	DTT	NGFR	5.08E-01	0.38	0.37

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1888).