Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM3DB8X)

Drug Name

Icariside II Drug Info

Synonyms

Baohuoside I; 113558-15-9; Icariside II; CHEBI:82619; Icarlin II; Baohuoside-I; Baohuoside I;; Icarisid II;; AC1NUQWY; 3,5,7-Trihydroxy-4'-methoxyl-8-prenylflavone-3-O-rhamnopyranoside; SCHEMBL4229321; CHEMBL560116; DTXSID40150457; 2h44; MolPort-020-006-007; HY-N0011; ZINC70455423; C27H30O10; CS-3673; 4H-1-Benzopyran-4-one, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-; AK169968; anhydroicaritin-3-O-alpha-L-rhamnopyranoside; N2538; Y0106; FT-0686579; Q-100071

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 5488822
ChEBI ID: CHEBI:82619
CAS Number: CAS 113558-15-9
TTD Drug ID: DM3DB8X

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Phosphodiesterase 5A (PDE5A)	TTJ0IQB	PDE5A_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Phosphodiesterase 5A (PDE5A)	DTT	PDE5A	3.632	3	3.632	4.271

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Phosphodiesterase 5A (PDE5A)	DTT	PDE5A	1.60E-01	-0.25	-0.99

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Potent inhibition of human phosphodiesterase-5 by icariin derivatives. J Nat Prod. 2008 Sep;71(9):1513-7.