Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM3PC0J)

Drug Name

N-8295 Drug Info

Synonyms

Universal flu vaccine; M2e-ISS; NP-ISS; ISS vaccine (influenza), Dynavax; M2e/NP-ISS; Influenza vaccine (immunostimulatory sequence-based), Dynavax; Influenza vaccine (ND-ISS-based), Dynavax

Indication

Disease Entry	ICD 11	Status	REF
Influenza virus infection	1E30-1E32	Phase 1	[1]

Cross-matching ID

TTD Drug ID: DM3PC0J

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Toll-like receptor 9 (TLR9)	TTSHG0T	TLR9_HUMAN	Not Available	[2]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Influenza virus infection

ICD Disease Classification

1E30-1E32

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Toll-like receptor 9 (TLR9)	DTT	TLR9	2.58E-01	-0.06	-0.17

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Clinical pipeline report, company report or official report of Dynavax Technologies Corp.
2	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019871)