Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM4CF18)

Drug Name

Menotropins Drug Info

Synonyms

Humegon; Human Menopausal Gonadotrophin; Human Menopausal Gonadotrophin (JP15); Humegon (TN); Menotropins (USP)

Indication

Disease Entry	ICD 11	Status	REF
Female infertility	GA31.Z	Approved	[1]

Therapeutic Class

Fertility Agents

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Follicle-stimulating hormone receptor (FSHR)	TTZFDBT	FSHR_HUMAN	Binder	[2]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Follicle-stimulating hormone receptor (FSHR)	DTT	FSHR	3.233	3.945	3.392	4.426

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Female infertility

ICD Disease Classification

GA31.Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Follicle-stimulating hormone receptor (FSHR)	DTT	FSHR	1.56E-02	-0.56	-1.34

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 020328.
2	The role of gonadotropins in ovulation induction. Am J Obstet Gynecol. 1995 Feb;172(2 Pt 2):759-65.