Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM4F8AU)

Drug Name
HuCART-meso cells Drug Info
Indication
Disease Entry ICD 11 Status REF
Lymphatic disease BD9Z Phase 1 [1]
Pancreatic cancer 2C10 Phase 1 [1]
Pediatric cancer 2A00-2F9Z Phase 1 [1]
Cross-matching ID
TTD Drug ID
DM4F8AU

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Mesothelin (MSLN) TT4RXME MSLN_HUMAN CAR-T-Cell-Therapy [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Mesothelin (MSLN) DTT MSLN -0.515 2.233 -0.152 0
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Lymphatic disease
ICD Disease Classification BD9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Mesothelin (MSLN) DTT MSLN 1.35E-02 5.44 1.92
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT03323944) CAR T Cell Immunotherapy for Pancreatic Cancer