Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM4NQY6)

Drug Name

5-iodo-1H-indazole Drug Info

Synonyms

5-Iodo-1H-indazole; 55919-82-9; 5-IODOINDAZOLE; 5-IODO (1H)INDAZOLE; 5-iodanyl-1H-indazole; 1H-INDAZOLE, 5-IODO-; CHEMBL391348; AK-27902; 5-Iodo-1H-indazole, 95%; 5-Iodo(1H)indazole; 5-iodio-1H-indazole; PubChem20575; SCHEMBL264176; 5-IODO-(1H)-INDAZOLE; CTK5A4375; DTXSID00619590; CGCHCLICSHIAAM-UHFFFAOYSA-N; MolPort-000-004-505; BCP27249; CS-D1249; ZX-AT020681; KS-000003HB; OR2756; ANW-50835; ZINC14983580; CI-264; BDBM50209243; RW3195; AKOS007930518; QC-2142; CM10802; RP05949; PB10471; VI20054; TRA0057528; FCH1323980; AS-8203; CJ-14773

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 21894739
CAS Number: CAS 55919-82-9
TTD Drug ID: DM4NQY6

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Nitric-oxide synthase brain (NOS1)	TTZUFI5	NOS1_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Nitric-oxide synthase brain (NOS1)	DTT	NOS1	6.085	5.844	5.849	5.806

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Nitric-oxide synthase brain (NOS1)	DTT	NOS1	5.20E-01	0.02	0.07

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3177-80.