Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM4VWXI)

Drug Name
[131I]-Metuximab Drug Info
Indication
Disease Entry ICD 11 Status REF
Liver cancer 2C12 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DM4VWXI

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Basigin (BSG) TT5UJWD BASI_HUMAN Not Available [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Basigin (BSG) DTT BSG 6.931 9.095 8.853 7.66
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

ICD Disease Classification 02 Neoplasm
Disease Class ICD-11: 2C82 Prostate cancer
The Studied Tissue Liver tissue
The Studied Disease Liver cancer [ICD-11:2C82]
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Basigin (BSG) DTT BSG 3.88E-09 0.88 1.35
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT00819650) A Trial of Licartin for Preventing Tumor Recurrence After Liver Resection. U.S. National Institutes of Health.
2 Targeting radioimmunotherapy of hepatocellular carcinoma with iodine (131I) metuximab injection: clinical phase I/II trials. Int J Radiat Oncol Biol Phys. 2006 Jun 1;65(2):435-44.