Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM5PRLA)

Drug Name
Fasinumab Drug Info
Indication
Disease Entry ICD 11 Status REF
Chronic low back pain MG30.02 Phase 3 [1]
Neuropathic pain 8E43.0 Phase 3 [1]
Osteoarthritis FA00-FA05 Phase 3 [1]
Pain MG30-MG3Z Phase 3 [1]
Cross-matching ID
TTD Drug ID
DM5PRLA

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Nerve growth factor (NGF) TTDN3LF NGF_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Nerve growth factor (NGF) DTT NGF 3.307 3 3.621 2.511
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Chronic low back pain
ICD Disease Classification MG30.02
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Nerve growth factor (NGF) DTT NGF 5.57E-02 -0.06 -0.31
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)